ArticleJournal of cardiovascular development and disease2022
Infective Endocarditis: Predictive Factors for Diagnosis and Mortality in Surgically Treated Patients.
Article in Journal of cardiovascular development and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- EuroSCORE II: Current limitations and physiological gaps in risk stratification.Experimental physiology · 2026Review
- Nomogram for predicting mortality in hospitalized patients with infective endocarditis.Scientific reports · 2025Article
- Vegetation Length is Associated with Long-term Survival in Patients Treated Surgically for Infective Endocarditis.Reviews in cardiovascular medicine · 2024Article
- Clinical Features and Patient Outcomes in Infective Endocarditis with Surgical Indication: A Single-Centre Experience.Journal of cardiovascular development and disease · 2024Article
- Splenic Embolism in Infective Endocarditis: A Systematic Review of the Literature with an Emphasis on Radiological and Histopathological Diagnoses.Tropical medicine and infectious disease · 2024Review
- Embolic Events in Infective Endocarditis: A Comprehensive Review.Reviews in cardiovascular medicine · 2024Review
- Novel Hematological Parameters in the Assessment of the Extent of Cardiac Implantable Electronic Device-Related Infections.Journal of clinical medicine · 2023Article
- Mitral Valve Infective Endocarditis Associated With Prednisolone-Induced Immunosuppression: A Case Report.Cureus · 2023Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Diagnosis of infective endocarditis (IE) often is challenging, and mortality is high in such patients. Our goal was to characterize common diagnostic tools to enable a rapid and accurate diagnosis and to correlate these tools with mortality outcomes. Methods: Because of the possibility of including perioperative diagnostics, only surgically treated patients with suspected left-sided IE were included in this retrospective, monocentric study. A clinical committee confirmed the diagnosis of IE. Results: 201 consecutive patients (age 64 ± 13 years, 74% male) were finally diagnosed with IE, and 14 patients turned out IE-negative. Preoperative tests with the highest sensitivity for IE were positive blood cultures (89.0%) and transesophageal echocardiography (87.5%). In receiver operating characteristics, vegetation size revealed high predictive power for IE (AUC 0.800, p < 0.001) with an optimal cut-off value of 11.5 mm. Systemic embolism was associated with mortality, and N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) had predictive power for mortality. Conclusion: If diagnostic standard tools remain inconclusive, we suggest employing novel cut-off values to increase diagnostic accuracy and accelerate diagnosis. Patients with embolism or elevated NT-proBNP deserve a closer follow-up.
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