Evidence map›Paper›PMID 36547374›Full record

ArticleAnalytical chemistry2023

Differentiation of Isomeric, Nonseparable Carbohydrates Using Tandem-Trapped Ion Mobility Spectrometry-Mass Spectrometry.

Jusung Lee, Mengqi Chai, Christian Bleiholder

Abstract read
In one paragraph

Article in Analytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Antioxidant and Anti-Aging Activity ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Gas Phase Reactivity of Isomeric Hydroxylated Polychlorinated Biphenyls.Journal of the American Society for Mass Spectrometry · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jusung LeeDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306-4390, United States.ORCID 0000-0003-1721-9618
Mengqi ChaiDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306-4390, United States.ORCID 0000-0002-6363-0216
Christian BleiholderDepartment of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida 32306-4390, United States.ORCID 0000-0002-4211-1388

Funding

Elucidating the structural heterogeneity of differentially modified protein systems by tandem-ion mobility spectrometry / mass spectrometry methods.R01GM135682 · NIGMS · FLORIDA STATE UNIVERSITY · PI BLEIHOLDER, CHRISTIAN · 2019 to 2022
$1.3M
NIGMS NIH HHS R01 GM135682
6 · The paper itself

Abstract

Carbohydrates play important roles in biological processes, but their identification remains a significant analytical problem. While mass spectrometry has increasingly enabled the elucidation of carbohydrates, current approaches are limited in their abilities to differentiate isomeric carbohydrates when these are not separated prior to tandem-mass spectrometry analysis. This analytical challenge takes on increased relevance because of the pervasive presence of isomeric carbohydrates in biological systems. Here, we demonstrate that TIMS

Indexed as

Ion Mobility SpectrometryTandem Mass SpectrometryCarbohydratesIonsIsomerismCarbohydratesIons

Identifiers

PMID36547374
PMCPMC10126951

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.