Evidence map›Paper›PMID 36547344›Full record

ArticleGels (Basel, Switzerland)2022

Xerogels Morphology Details by Multifractal Analysis and Scanning Electron Microscopy Images Evaluations of 5-Fluorouracil Release from Chitosan-Based Matrix.

Maria-Alexandra Paun, Mihai-Virgil Nichita, Vladimir-Alexandru Paun, Viorel-Puiu Paun

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Maria-Alexandra PaunSchool of Engineering, Swiss Federal Institute of Technology (EPFL), 1015 Lausanne, Vaud, Switzerland.ORCID 0000-0003-2088-7457
Mihai-Virgil NichitaDoctoral School, Faculty of Applied Sciences, University Politehnica of Bucharest, 060042 Bucharest, Romania.ORCID 0000-0001-9099-4608
Vladimir-Alexandru PaunFive Rescue Research Laboratory, 75004 Paris, France.
Viorel-Puiu PaunPhysics Department, Faculty of Applied Sciences, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Academia Oamenilor de Știință din România · ROÉcole Polytechnique Fédérale de Lausanne · CHUniversitatea Națională de Știință și Tehnologie Politehnica București · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four medicament delivery formulations based on 5-fluorouracil in a chitosan substantial matrix were realized in situ via 3,7-dimethyl-2,6-octadienal element hydrogelation. Representative samples of the final realized compounds were investigated from an analytic, constitutional, and morphological viewpoint via Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM). The SEM images of the formulations were investigated in concordance with fractal analysis, and the fractal dimensions and lacunarity were computed. The developed mathematical multifractal model is necessarily confirmed by the experimental measurements corresponding to the 5-fluorouracil release outside the chitosan-formed matrix.

Indexed as

5-fluorouracilchitosan hydrogelsfractal analysismultifractal dynamicsSEM images

Identifiers

PMID36547344
PMCPMC9778206
OpenAlexW4311235917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.