Evidence map›Paper›PMID 36547320›Full record

ArticleGels (Basel, Switzerland)2022

Chitosan Aerogel Particles as Nasal Drug Delivery Systems.

Natalia Menshutina, Alexander Majouga, Anastasia Uvarova, Daria Lovskaya, Pavel Tsygankov, Maria Mochalova, Olga Abramova, Valeria Ushakova, Anna Morozova, Artemiy Silantyev

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Nose-to-brain drug delivery: from bench to bedside.Translational neurodegeneration · 2025
    Review
  7. Particulate bioaerogels for respiratory drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Natalia MenshutinaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, Moscow 125047, Russia.ORCID 0000-0001-7806-1426
Alexander MajougaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, Moscow 125047, Russia.
Anastasia UvarovaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, Moscow 125047, Russia.ORCID 0000-0003-4208-7063
Daria LovskayaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, Moscow 125047, Russia.ORCID 0000-0002-8709-4139
Pavel TsygankovDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, Moscow 125047, Russia.
Maria MochalovaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, Moscow 125047, Russia.ORCID 0000-0003-1200-8125
Olga AbramovaDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky per. 23, Moscow 119034, Russia.ORCID 0000-0001-8793-1833
Valeria UshakovaDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky per. 23, Moscow 119034, Russia.
Anna MorozovaDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky per. 23, Moscow 119034, Russia.
Artemiy SilantyevDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky per. 23, Moscow 119034, Russia.
D. Mendeleyev University of Chemical Technology of Russia · RUFederal Medical Research Centre for Psychiatry and Narcology · RU

Funding

Ministry of science and higher education of the Russian Federation 075-15-2020-792
6 · The paper itself

Abstract

The nasal drug delivery route has distinct advantages, such as high bioavailability, a rapid therapeutic effect, non-invasiveness, and ease of administration. This article presents the results of a study of the processes for obtaining chitosan aerogel particles that are promising as nasal or inhalation drug delivery systems. Obtaining chitosan aerogel particles includes the following steps: the preparation of a chitosan solution, gelation, solvent replacement, and supercritical drying. Particles of chitosan gels were obtained by spraying and homogenization. The produced chitosan aerogel particles had specific surface areas of up to 254 m

Indexed as

aerogelchitosandrug delivery systemshomogenizationin vivo experimentsparticlespharmacokineticsspraying

Identifiers

PMID36547320
PMCPMC9778004
OpenAlexW4311626873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.