Evidence map›Paper›PMID 36547301›Full record

ReviewGels (Basel, Switzerland)2022

Advancements in Hydrogel Application for Ischemic Stroke Therapy.

Ying Bai, Bing Han, Yi Zhang, Yuan Zhang, Yang Cai, Ling Shen, Yanpeng Jia

Open access · goldAbstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Dynamic Hydrogels in Breast Tumor Models.Gels (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ying BaiDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing 210009, China.ORCID 0000-0002-5514-6280
Bing HanDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing 210009, China.ORCID 0000-0001-8170-498X
Yi ZhangDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing 210009, China.
Yuan ZhangDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing 210009, China.
Yang CaiDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing 210009, China.ORCID 0000-0001-7700-9781
Ling ShenDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing 210009, China.
Yanpeng JiaDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing 210009, China.
Southeast University · CN

Funding

the National Natural Science Foundation of China 32101071, 82230115, 82025033, 81903591, 82003733
6 · The paper itself

Abstract

Ischemic stroke is a major cause of death and disability worldwide. There is almost no effective treatment for this disease. Therefore, developing effective treatment for ischemic stroke is urgently needed. Efficient delivery of therapeutic drugs to ischemic sites remained a great challenge for improved treatment of strokes. In recent years, hydrogel-based strategies have been widely investigated for new and improved therapies. They have the advantage of delivering therapeutics in a controlled manner to the poststroke sites, aiming to enhance the intrinsic repair and regeneration. In this review, we discuss the pathophysiology of stroke and the development of injectable hydrogels in the application of both stroke treatment and neural tissue engineering. We also discuss the prospect and the challenges of hydrogels in the treatment of ischemic strokes.

Indexed as

biomaterialsdrug deliveryhydrogelischemic strokeregeneration

Identifiers

PMID36547301
PMCPMC9778209
OpenAlexW4310142255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.