Evidence map›Paper›PMID 36547292›Full record

ReviewGels (Basel, Switzerland)2022

Hydrogel-Based Biosensors.

Katharina Völlmecke, Rowshon Afroz, Sascha Bierbach, Lee Josephine Brenker, Sebastian Frücht, Alexandra Glass, Ryland Giebelhaus, Axel Hoppe, Karen Kanemaru, Michal Lazarek and 6 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
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  11. OGels (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Katharina VöllmeckeDepartment of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany.
Rowshon AfrozDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, AB T6G 2G2, Canada.
Sascha BierbachDepartment of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany.
Lee Josephine BrenkerDepartment of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany.
Sebastian FrüchtDepartment of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany.ORCID 0000-0003-0335-5248
Alexandra GlassDepartment of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany.
Ryland GiebelhausDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, AB T6G 2G2, Canada.ORCID 0000-0002-7625-3077
Axel HoppeDepartment of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany.
Karen KanemaruDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, AB T6G 2G2, Canada.ORCID 0000-0002-0857-4805
Michal LazarekDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, AB T6G 2G2, Canada.ORCID 0000-0001-8753-7510
Lukas RabbeDepartment of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany.
Longfei SongDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, AB T6G 2G2, Canada.ORCID 0000-0001-7421-9687
Andrea Velasco SuarezDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, AB T6G 2G2, Canada.ORCID 0000-0002-2726-188X
Shuang WuDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, AB T6G 2G2, Canada.ORCID 0000-0001-6374-198X
Michael SerpeDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, AB T6G 2G2, Canada.
Dirk KucklingDepartment of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany.ORCID 0000-0001-6003-151X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an increasing interest in sensing applications for a variety of analytes in aqueous environments, as conventional methods do not work reliably under humid conditions or they require complex equipment with experienced operators. Hydrogel sensors are easy to fabricate, are incredibly sensitive, and have broad dynamic ranges. Experiments on their robustness, reliability, and reusability have indicated the possible long-term applications of these systems in a variety of fields, including disease diagnosis, detection of pharmaceuticals, and in environmental testing. It is possible to produce hydrogels, which, upon sensing a specific analyte, can adsorb it onto their 3D-structure and can therefore be used to remove them from a given environment. High specificity can be obtained by using molecularly imprinted polymers. Typical detection principles involve optical methods including fluorescence and chemiluminescence, and volume changes in colloidal photonic crystals, as well as electrochemical methods. Here, we explore the current research utilizing hydrogel-based sensors in three main areas: (1) biomedical applications, (2) for detecting and quantifying pharmaceuticals of interest, and (3) detecting and quantifying environmental contaminants in aqueous environments.

Indexed as

biomarkerbiosensorDNAdrugenvironmental pollutanthydrogelprotein

Identifiers

PMID36547292
PMCPMC9777866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.