Evidence map›Paper›PMID 36547289›Full record

ArticleGels (Basel, Switzerland)2022

Preparation of Protein Aerogel Particles for the Development of Innovative Drug Delivery Systems.

Daria Lovskaya, Anna Bezchasnyuk, Maria Mochalova, Pavel Tsygankov, Artem Lebedev, Yana Zorkina, Eugene Zubkov, Aleksandra Ochneva, Olga Gurina, Artemiy Silantyev and 2 more

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Particulate bioaerogels for respiratory drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Daria LovskayaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, 125047 Moscow, Russia.ORCID 0000-0002-8709-4139
Anna BezchasnyukDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, 125047 Moscow, Russia.
Maria MochalovaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, 125047 Moscow, Russia.ORCID 0000-0003-1200-8125
Pavel TsygankovDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, 125047 Moscow, Russia.
Artem LebedevDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, 125047 Moscow, Russia.ORCID 0000-0002-6765-7563
Yana ZorkinaDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky Per. 23, 119034 Moscow, Russia.ORCID 0000-0003-0247-2717
Eugene ZubkovDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky Per. 23, 119034 Moscow, Russia.
Aleksandra OchnevaDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky Per. 23, 119034 Moscow, Russia.
Olga GurinaDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky Per. 23, 119034 Moscow, Russia.
Artemiy SilantyevDepartment of Basic and Applied Neurobiology, V. Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Kropotkinsky Per. 23, 119034 Moscow, Russia.
Alexander MajougaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, 125047 Moscow, Russia.
Natalia MenshutinaDepartment of Chemical and Pharmaceutical Engineering, Mendeleev University of Chemical Technology, 125047 Moscow, Russia.ORCID 0000-0001-7806-1426
D. Mendeleyev University of Chemical Technology of Russia · RUFederal Medical Research Centre for Psychiatry and Narcology · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2020-792
6 · The paper itself

Abstract

The research was oriented towards the preparation of aerogel particles based on egg white and whey protein isolate using various dispersion methods: dripping, spraying, and homogenization. Based on the results of analytical studies, the most appropriate samples were selected to obtain aerogels loaded with the drug. The results of the experimental research were used to study methods for obtaining nasal drug delivery systems based on aerogels. Protein aerogels were obtained by thermal gelation followed by supercritical drying. The obtained particles of protein aerogels have a specific surface area of up to 350 m

Indexed as

aerogelbioavailabilityclomipraminein vivo evaluationsnasal drug delivery systempharmacokineticsprotein

Identifiers

PMID36547289
PMCPMC9777701
OpenAlexW4310043636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.