ArticleGeriatrics (Basel, Switzerland)2022
Polypharmacy Patterns in Multimorbid Older People with Cardiovascular Disease: Longitudinal Study.
Article in Geriatrics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- Dispensing of actionable pharmacogenetic drugs among adults receiving cardiovascular disease medications in the Northern Netherlands: A serial cross-sectional study.Clinical pharmacology and therapeutics · 2026Article
- Development and Validation of an XGBoost-SHAP Model for Predicting Adverse Outcomes in Elderly Cardiovascular Patients With Polypharmacy: A Retrospective Cohort Study.Pharmacology research & perspectives · 2026Article
- Availability, price and affordability of essential medicines for managing cardiovascular disease in Addis Ababa, Ethiopia.Scientific reports · 2024Article
- Trajectories of chronic multimorbidity patterns in older patients: MTOP study.BMC geriatrics · 2024Observational
- Safety of combined drug use in patients with cardiovascular and cerebrovascular diseases: an analysis based on the spontaneous reporting database of adverse drug reactions in Hubei Province.Frontiers in pharmacology · 2024Article
- A comprehensive review of machine learning algorithms and their application in geriatric medicine: present and future.Aging clinical and experimental research · 2023Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
(1) Introduction: Cardiovascular disease is associated with high mortality, especially in older people. This study aimed to characterize the evolution of combined multimorbidity and polypharmacy patterns in older people with different cardiovascular disease profiles. (2) Material and methods: This longitudinal study drew data from the Information System for Research in Primary Care in people aged 65 to 99 years with profiles of cardiovascular multimorbidity. Combined patterns of multimorbidity and polypharmacy were analysed using fuzzy c-means clustering techniques and hidden Markov models. The prevalence, observed/expected ratio, and exclusivity of chronic diseases and/or groups of these with the corresponding medication were described. (3) Results: The study included 114,516 people, mostly men (59.6%) with a mean age of 78.8 years and a high prevalence of polypharmacy (83.5%). The following patterns were identified:
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