Does Estimated Glomerular Filtration Rate Predict In-Hospital Mortality in Acutely Unwell Hospitalized Oldest Old?

Zack Robert Wakerly, Roy L Soiza, Tiberiu A Pana, Phyo Kyaw Myint

Open access · goldAbstract read

In one paragraph

Article in Geriatrics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 43% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zack Robert WakerlyAgeing Clinical & Experimental Research Team (ACER), Institute of Applied health Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.

Roy L SoizaAgeing Clinical & Experimental Research Team (ACER), Institute of Applied health Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.ORCID 0000-0002-1397-4272

Tiberiu A PanaAgeing Clinical & Experimental Research Team (ACER), Institute of Applied health Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.

Phyo Kyaw MyintAgeing Clinical & Experimental Research Team (ACER), Institute of Applied health Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.ORCID 0000-0003-3852-6158

National Health Service · GBUniversity of Aberdeen · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally the population of older adults is the fastest growing age group. Estimated glomerular filtration rate (eGFR) is an estimation of true kidney function with lower eGFR associated with higher mortality. However, few studies explore eGFR's prognostic value in the nonagenarian. We investigated the association between eGFR on admission and mortality among the nonagenarians hospitalised with acute illness. A retrospective analysis of a prospective cohort study included patients aged ≥ 90 admitted into three acute medical assessment units or acute geriatric wards in England and Scotland between November 2008 and January 2009. Association between eGFR and all-cause mortality was evaluated using the Cox proportional hazard models controlling for potential confounders including frailty. 392 patients with mean (SD) 93.0 ± 2.6 years (68.45% women) were included. The median (IQR) eGFR was 26.61 (18.41-40.41) mL/min/1.73

Indexed as

CKDeGFRfrailtyoldest old

Identifiers

PMID36547271

DOI10.3390/geriatrics7060135

PMCPMC9777760

OpenAlexW4310075664

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.