Evidence map›Paper›PMID 36547231›Full record

ArticleNanomedicine (London, England)2022

Pharmacokinetics and tissue distribution of deferoxamine-based nanochelator in rats.

Gregory Jones, Lingxue Zeng, Wesley R Stiles, Seung Hun Park, Homan Kang, Hak Soo Choi, Jonghan Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomedicine (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Ferroptosis inhibitors: past, present and future.Frontiers in pharmacology · 2024
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gregory JonesDepartment of Pharmaceutical Sciences, Bouve College of Health Sciences, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0003-0514-8859
Lingxue ZengDepartment of Biomedical & Nutritional Sciences, Zuckerberg College of Health Sciences, University of Massachusetts Lowell, Lowell, MA 01854, USA.ORCID 0000-0002-7399-2376
Wesley R StilesDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA.
Seung Hun ParkDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-8899-0138
Homan KangDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-0732-9779
Hak Soo ChoiDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-7982-6483
Jonghan KimDepartment of Biomedical & Nutritional Sciences, Zuckerberg College of Health Sciences, University of Massachusetts Lowell, Lowell, MA 01854, USA.ORCID 0000-0001-8226-7427

Funding

Nanochelation Therapies for Iron Overload DisordersR01HL143020 · NHLBI · UNIVERSITY OF MASSACHUSETTS LOWELL · PI CHOI, HAK SOO, KIM, JONGHAN · 2018 to 2021
$2.6M
NHLBI NIH HHS R01 HL143020
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DeferoxamineIron OverloadAnimalsIron Chelating AgentsRatsRats, Sprague-DawleyTissue DistributionDeferoxamineIron Chelating Agentsabsorption-rate limited kineticsiron chelatornonlinear pharmacokineticsrenal clearancesaturable reabsorption

Identifiers

PMID36547231
PMCPMC9869290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.