Evidence map›Paper›PMID 36547198›Full record

ReviewDiseases (Basel, Switzerland)2022

Efficacy and Safety of COVID-19 Vaccines-An Update.

Eshani Sharma, Sraddha Revinipati, Saisha Bhandari, Sejal Thakur, Shubham Goyal, Aruni Ghose, Sukrit Bajpai, Waleed Muhammad, Stergios Boussios

Open access · goldAbstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Vaccination and Therapeutics.Advances in experimental medicine and biology · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. COVID-19: Where We Are and Where We Are Going.Diseases (Basel, Switzerland) · 2023
    Article
  11. Health and Well-Being through COVID-19 Vaccination: Physical, Oral, and Psychological Effects.International journal of environmental research and public health · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Eshani SharmaDepartment of Internal Medicine, Kasturba Medical College, Mangalore 575001, India.ORCID 0000-0001-6052-9131
Sraddha RevinipatiMGM Institute of Health Sciences, Navi Mumbai 410209, India.ORCID 0000-0002-5878-7913
Saisha BhandariDepartment of Internal Medicine, Kasturba Medical College, Mangalore 575001, India.
Sejal ThakurDepartment of Internal Medicine, Kasturba Medical College, Mangalore 575001, India.ORCID 0000-0002-6110-2532
Shubham GoyalDepartment of Infectious Diseases, Kasturba Medical College, Manipal 576104, India.
Aruni GhoseDepartment of Internal Medicine, Newham University Hospital, Barts Health NHS Trust, London E13 8SL, UK.ORCID 0000-0001-8332-8033
Sukrit BajpaiDepartment of Respiratory Medicine, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
Waleed MuhammadDepartment of Internal Medicine, Newham University Hospital, Barts Health NHS Trust, London E13 8SL, UK.
Stergios BoussiosDepartment of Medical Oncology, Medway NHS Foundation Trust, Windmill Road, Gillingham ME7 5NY, UK.ORCID 0000-0002-2512-6131
Kasturba Medical College, Mangalore · INBarts Health NHS Trust · GBKasturba Medical College, Manipal · INKing's College London · GBMahatma Gandhi Mission Institute of Health Sciences · INUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A few centuries ago, the first vaccine vial was formulated, and since then, they have resulted in an eminent reduction in infectious diseases associated morbidity and mortality. The discovery of the novel SARS-CoV-2 virus and the COVID-19 disease and its steady progression to a global pandemic with 603,711,760 confirmed cases and 6,484,136 reported deaths according to the World Health Organization (WHO) on 7 September 2022 was exceedingly catastrophic. This brought about an unexpected need for preventative and cost-effective measures to curb the devastating impact of the virus, followed by accelerated competition within the pharma giants to manufacture and dispense vaccines at an exponential rate. Non-pharmaceutical medications such as mandated face mask policies, the imposition of travel limitations and generalized disinfectant use were somewhat successful in mitigating the catastrophic effect, but the onus fell upon vaccination strategies and other medical interventions to counteract and subdue this international health threat. The need to ensure current and future pandemic preparedness, however, presents multiple hurdles, among which are equitable vaccine access and the rising trend of vaccine hesitancy at an individual and international level, which are beyond the scope of this discussion. With this review article, we seek to draw perspective on current COVID-19 virus variants, in-hand vaccine types with their mechanism of action along with their effectiveness and safety profile. We also aim to discuss substantial side effects while adding a segment on the booster dose controversy.

Indexed as

COVID-19efficacysafetySARS-CoV-2vaccine

Identifiers

PMID36547198
PMCPMC9777372
OpenAlexW4309882530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.