ArticleCurrent oncology (Toronto, Ont.)2022
Thin Cartilage Cap May Be Related to the Spontaneous Regression in Pediatric Patients with Osteochondroma.
Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Vanishing Osteochondromas of the Distal Femur and Proximal Humerus: A Two-Case Report.Journal of orthopaedic case reports · 2026Article
- Investigating possible predictors of malignant transformation of osteochondroma: a retrospective cohort study with an illustrative case report.Skeletal radiology · 2026Article
- The most common bone tumors of the upper extremity in childhood and adolescence and their treatment: a review of the current literature.EFORT open reviews · 2026Review
- Spontaneous Regression of Pediatric Osteochondroma: Clinical Case and Comprehensive Literature Review.Cureus · 2025Article
- Spontaneous Regression of Multiple Osteochondromas in a Patient With Hereditary Multiple Exostoses: A Case Report.Cureus · 2025Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe spontaneous regression of osteochondromas is rare, and only a few cases have been reported. Furthermore, the precise mechanism underlying spontaneous regression is unknown. This study aimed to examine the radiological findings of osteochondromas that had spontaneous regression and to identify potential indicators of this uncommon phenomenon in skeletally immature patients with osteochondromas.
methodsWe included 28 patients (15 males and 13 females) who met the eligibility criteria between 2002 and 2019. The mean age at initial diagnosis was 9.7 years old (2-16 years). The mean follow-up period was 6.4 years (3-16 years).
resultsOf the 28 patients, 10 (35.7%) had osteochondroma resolution. The osteochondroma resolved in one patient and regressed in nine. Tumor shrinkage is related to the thickness of the cartilage cap. The thickness of the cartilage cap did not correlate with age.
conclusionsTumor shrinkage is associated with a thinner cartilage cap on magnetic resonance imaging. The thickness of the cartilage cap may be an important predictor of spontaneous regression in pediatric patients with osteochondroma.
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