Evidence map›Paper›PMID 36547166›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services' Cord Blood Bank: First Analysis.

Gaganvir Parmar, Meagan Green, Karen Mostert, Tiffany Lawless, Nicholas Dibdin, Jason Weiss, Kathy Ganz, Tanya Petraszko, Matthew D Seftel, David S Allan

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Gaganvir ParmarStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Meagan GreenStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Karen MostertStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Tiffany LawlessStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Nicholas DibdinStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Jason WeissStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Kathy GanzStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Tanya PetraszkoStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Matthew D SeftelStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
David S AllanStem Cells, Canadian Blood Services, Ottawa, ON K2E 8A6, Canada.
Canadian Blood Services · CAOttawa Hospital Research InstituteUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Canadian Blood Services Cord Blood Bank (CBS CBB) was created to improve access to stem cell products for transplantation for patients across ethnic groups. An analysis of distributed units is needed to assess the effectiveness of the bank to meet the needs of patients from different ethnic groups.

methodsA descriptive analysis was performed on all cord blood units distributed from the CBS' CBB as of 30 June 2022.

resultsDistribution of the first 60 units based on CBS' CBB inventory has been linear over time. A similar proportion of cord blood unit (CBU) recipients were pediatric or adult. More than half of the cord blood units (56.7%) were distributed to recipients outside of Canada, and CBUs were used to treat a broad range of hematologic and immune disorders. 43.3% of distributed CBUs were of non-Caucasian ethnicity and 18% were from donors self-reporting as multi-ethnic. The mean total nucleated cell counts and total CD34

conclusionsThe CBS' CBB has facilitated the utilization of banked units for patients across a broad range of ages, geographic distribution, ethnicity, and diseases. Distributed units were well matched for HLA alleles and contained robust cell counts, reflecting a high-quality inventory with significant utility.

Indexed as

Blood BanksCord Blood Stem Cell TransplantationFetal BloodAdolescentAdultAllelesCanadaChildChild, PreschoolHLA AntigensHumansInfantInfant, NewbornHLA Antigenscord blood bankingethnicityhematopoietictransplantation

Identifiers

PMID36547166
PMCPMC9777040
OpenAlexW4311636670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.