Evidence map›Paper›PMID 36547157›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Comparison of Efficacy and Safety of Platinum-Based Chemotherapy as First-Line Therapy between B3 Thymoma and Thymic Carcinoma.

Yue Hao, Jinfei Si, Jianan Jin, Jingwen Wei, Jing Xiang, Chunwei Xu, Zhengbo Song

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yue HaoThe Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310000, China.ORCID 0000-0002-4725-6084
Jinfei SiThe Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310000, China.ORCID 0000-0001-6351-1690
Jianan JinDepartment of Clinical Trial, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou 310022, China.ORCID 0000-0002-9903-9276
Jingwen WeiDepartment of Clinical Trial, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou 310022, China.
Jing XiangThe Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310000, China.
Chunwei XuDepartment of Respiratory Medicine, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210093, China.ORCID 0000-0002-9021-6731
Zhengbo SongDepartment of Clinical Trial, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou 310022, China.
Zhejiang Cancer Hospital · CNZhejiang Chinese Medical University · CNNanjing General Hospital of Nanjing Military Command · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundB3 type thymoma is defined as a well-differentiated thymic carcinoma and is similar to a thymic carcinoma. However, the differences between them are not well defined. In addition, the data to compare the efficacy and safety of platinum-based chemotherapy as first-line therapy between B3 thymoma and thymic carcinoma are lacking.

methodsThe efficacy and safety of platinum-based chemotherapy as first-line therapy was retrospectively compared between a group of 36 patients with type B3 thymoma and a group of 127 patients with thymic carcinoma treated between January 2009 and March 2022 at the Zhejiang Cancer Hospital. Objective response rate (ORR), progression-free survival (PFS), overall survival (OS), and treatment-related adverse events were analyzed.

resultsThe ORRs for B3 thymoma and thymic carcinoma were 36.1% and 28.3%, respectively (

conclusionsB3 thymoma and especially squamous carcinoma patients may be treated using a similar therapy scheme as that utilized for thymic carcinoma.

Indexed as

Carcinoma, Squamous CellThymomaThymus NeoplasmsHumansPlatinumRetrospective StudiesPlatinumB3 thymomaefficacyplatinum-based chemotherapysafetythymic carcinoma

Identifiers

PMID36547157
PMCPMC9776500
OpenAlexW4311554400

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.