Evidence map›Paper›PMID 36547138›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Inflammatory Ratios as Predictors for Tumor Invasiveness, Metastasis, Resectability and Early Postoperative Evolution in Gastric Cancer.

Vlad I Nechita, Nadim Al-Hajjar, Emil Moiş, Luminiţa Furcea, Mihaela A Nechita, Florin Graur

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Investigating the predictive role of inflammatory indices in cancer metastasis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  2. Article
  3. Prognostic value of changes in pre- and postoperative inflammatory blood markers in HPV-negative head and neck squamous cell carcinomas.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vlad I NechitaDepartment of Medical Informatics and Biostatistics, "Iuliu Hațieganu" University of Medicine and Pharmacy, Louis Pasteur Str., No. 6, 400349 Cluj-Napoca, Romania.
Nadim Al-Hajjar"Octavian Fodor" Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19-21, 400162 Cluj-Napoca, Romania.
Emil Moiş"Octavian Fodor" Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19-21, 400162 Cluj-Napoca, Romania.ORCID 0000-0002-2972-3777
Luminiţa Furcea"Octavian Fodor" Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19-21, 400162 Cluj-Napoca, Romania.
Mihaela A Nechita"Ion Chiricuță" Oncology Institute, Republicii Str., No.34-36, 400015 Cluj-Napoca, Romania.
Florin Graur"Octavian Fodor" Regional Institute of Gastroenterology and Hepatology, Croitorilor Str., No. 19-21, 400162 Cluj-Napoca, Romania.ORCID 0000-0002-5887-3408

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study aimed to evaluate the baseline neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and systemic immune-inflammation index (SII) in relation to invasion, metastasis, and resectability for patients with gastric cancer, respectively, as predictors of death during hospitalization or surgical complications. A retrospective cohort study was conducted on 657 gastric cancer subjects. Inflammatory biomarkers were computed. The associations with tumor stage, metastasis, optimal procedure, in-hospital mortality, and surgical complications were evaluated. Subjects who underwent curative-intent surgery presented lower median NLRs (2.9 vs. 3.79), PLRs (166.15 vs. 196.76), and SIIs (783.61 vs. 1122.25), and higher LMRs (3.34 vs. 2.9) than those who underwent palliative surgery. Significantly higher NLRs (3.3 vs. 2.64), PLRs (179.68 vs. 141.83), and SIIs (920.01 vs. 612.93) were observed for those with T3- and T4-stage cancer, in comparison with those with T1- and T2-stage cancer. Values were significantly higher in the case of metastasis for the NLR (3.96 vs. 2.93), PLR (205.22 vs. 167.17), and SII (1179 vs. 788.37) and significantly lower for the LMR (2.74 vs. 3.35). After the intervention, the NLR, PLR, and SII values were higher (

Indexed as

Stomach NeoplasmsBiomarkersBlood PlateletsHumansLymphocytesRetrospective StudiesBiomarkerscurative surgerygastric cancerinflammatory biomarkerslymphocyte-to-monocyte ratio (LMR)neutrophil-to-lymphocyte ratio (NLR)palliative treatmentplatelet-to-lymphocyte ratio (PLR)systemic immune-inflammation index (SII)

Identifiers

PMID36547138
PMCPMC9776857

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.