Evidence map›Paper›PMID 36547089›Full record

ArticleCurrent issues in molecular biology2022

An Exploratory In Vivo Study on the Effect of Annurca Apple Extract on Hair Growth in Mice.

Young In Lee, Seoyoon Ham, Sang Gyu Lee, Inhee Jung, Jangmi Suk, Jinhee Yoo, Su-Young Choi, Ju Hee Lee

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Young In LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-6831-7379
Seoyoon HamDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Sang Gyu LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-6237-9031
Inhee JungGlobal Medical Research Center, Seoul 06526, Republic of Korea.
Jangmi SukGlobal Medical Research Center, Seoul 06526, Republic of Korea.
Jinhee YooCOSMAX NBT, INC, c-601, 25, Pangyo-ro 256beon-gil, Bundang-gu, Seongnam-si 18622, Gyeonggi-do, Republic of Korea.
Su-Young ChoiCOSMAX NBT, INC, c-601, 25, Pangyo-ro 256beon-gil, Bundang-gu, Seongnam-si 18622, Gyeonggi-do, Republic of Korea.
Ju Hee LeeDepartment of Dermatology & Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Yonsei University · KRSeoul Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hair loss is an important problem affecting the quality of life in modern society. Recent studies show that Annurca apple extract (AAE), enriched in procyanidin B2 and nutraceuticals, promotes hair growth and induces keratin production. In this study, we investigated the effects of AAE by orally administering AAE in six-week-old C57BL/6 mice once a day for 21 d. We observed improvement in hair length, thickness, weight, and density. The gene expression of two growth factors related to hair growth, vascular endothelial growth factor A (

Indexed as

annurca apple extractcytokeratinhair growth factorshair losspolyphenols

Identifiers

PMID36547089
PMCPMC9776982
OpenAlexW4312128061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.