ArticleBiomimetics (Basel, Switzerland)2022
Facile Fabrication of Methyl Gallate Encapsulated Folate ZIF-L Nanoframeworks as a pH Responsive Drug Delivery System for Anti-Biofilm and Anticancer Therapy.
Article in Biomimetics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- A Green, Solvent- and Cation-Free Approach for Preparing 5-Fluorouracil-Loaded Alginate Nanoparticles Using Microfluidic Technology.Pharmaceutics · 2025Article
- Antibacterial activity of gallic acid and methyl gallate against emerging non-fermenting bacilli.Folia microbiologica · 2025Article
- Antibacterial and antibiofilm activities of ZIF-67.The Journal of antibiotics · 2023Article
- Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3'-oxindoles] under Microwave Irradiation and Their Anticancer Activity.Molecules (Basel, Switzerland) · 2023Article
- Combating Microbial Infections Using Metal-Based Nanoparticles as Potential Therapeutic Alternatives.Antibiotics (Basel, Switzerland) · 2023Review
- Development of a Polyherbal Topical Gel for the Treatment of Acne.Gels (Basel, Switzerland) · 2023Article
- Highly efficient degradation of reactive black KN-B dye by ultraviolet light responsive ZIF-8 photocatalysts with different morphologies.RSC advances · 2023Article
- Taste Masking of Promethazine Hydrochloride Using l-Arginine Polyamide-Based Nanocapsules.Molecules (Basel, Switzerland) · 2023Article
- Smart Pellets for Controlled Delivery of 5-Fluorouracil.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
Zeolitic imidazole frameworks are emerging materials and have been considered an efficient platform for biomedical applications. The present study highlights the simple fabrication of methyl gallate encapsulated folate-ZIF-L nanoframeworks (MG@Folate ZIF-L) by a simple synthesis. The nanoframeworks were characterized by different sophisticated instruments. In addition, the drug-releasing mechanism was evidenced by in vitro releasing kinetics at various pH conditions. The anti-biofilm potential confirmed by the biofilm architectural deformations against human infectious pathogens MRSA and N7 clinical strains. Furthermore, anticancer efficacy assessed against A549 lung cancer cells. The result reveals that the MG@Folate ZIF-L exposed a superior cytotoxic effect due to the pH-responsive and receptor-based drug-releasing mechanism. Based on the unique physicochemical and biological characteristics of nanoframeworks, it has overcome the problems of undesired side effects and uncontrolled drug release of existing drug delivery systems. Finally, the in vitro toxicity effect of MG@Folate ZIF-L was tested against the
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