Evidence map›Paper›PMID 36546900›Full record

ArticleAntibodies (Basel, Switzerland)2022

Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies Using Flow Cytometry.

Nami Tateyama, Teizo Asano, Hiroyuki Suzuki, Guanjie Li, Takeo Yoshikawa, Tomohiro Tanaka, Mika K Kaneko, Yukinari Kato

Open access · goldAbstract read
In one paragraph

Article in Antibodies (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. A novel anti-mouse CXCR1 monoclonal antibody, CxBiochemistry and biophysics reports · 2025
    Article
  3. Development of an anti-human EphA2 monoclonal antibody EaBiochemistry and biophysics reports · 2025
    Article
  4. A novel anti-mouse CCR7 monoclonal antibody, CBiochemistry and biophysics reports · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nami TateyamaDepartment of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Teizo AsanoDepartment of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0002-4784-0141
Hiroyuki SuzukiDepartment of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0003-2646-5132
Guanjie LiDepartment of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Takeo YoshikawaDepartment of Pharmacology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0002-7056-6021
Tomohiro TanakaDepartment of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Mika K KanekoDepartment of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.
Yukinari KatoDepartment of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan.ORCID 0000-0001-5385-8201
Tohoku University · JP

Funding

Japan Agency for Medical Research and Development JP22ama121008, JP21am0401013, JP22bm1004001, JP22ck0106730, JP21am0101078
6 · The paper itself

Abstract

The CC chemokine receptor 3 (CCR3) is a receptor for CC chemokines, including CCL5/RANTES, CCL7/MCP-3, and CCL11/eotaxin. CCR3 is expressed on the surface of eosinophils, basophils, a subset of Th2 lymphocytes, mast cells, and airway epithelial cells. CCR3 and its ligands are involved in airway hyperresponsiveness in allergic asthma, ocular allergies, and cancers. Therefore, CCR3 is an attractive target for those therapies. Previously, anti-mouse CCR3 (mCCR3) monoclonal antibodies (mAbs), C

Indexed as

alanine scanningepitope mappingflow cytometrymonoclonal antibodymouse CCR3

Identifiers

PMID36546900
PMCPMC9774254
OpenAlexW4311533646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.