ArticleBJS open2022
Surviving rectal cancer at the cost of a colostomy: global survey of long-term health-related quality of life in 10 countries.
Article in BJS open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Prioritizing Chemotherapy in Total Neoadjuvant Therapy Improves pCR Rate in Locally Advanced Rectal Cancer in Countries with Limited Radiotherapy Access: A Randomized Controlled Trial.Journal of gastrointestinal cancer · 2026Trial
- Postoperative Function and Quality of Life of Patients With Low Rectal Cancer: A Multidimensional Comparison Between Low Anterior Resection and Abdominoperineal Resection.World journal of surgery · 2026Article
- The Role of Family Care on the Quality of Life of Patients With Permanent Enterostomies: A Chain-Mediated Effect of Inner Strength and Patient Activation.Scandinavian journal of caring sciences · 2026Article
- Successful Stereotactic Body Radiation Therapy for Prostate Cancer in a Patient With Prior Total Colectomy and Ileal Pouch-Anal Anastomosis: A Case Report and Technical Considerations.Advances in radiation oncology · 2026Article
- A scoping review on social isolation in patients with intestinal stomas.Frontiers in psychology · 2026Review
- Prognostic factors affecting survival in patients with duodenal adenocarcinoma and isolated liver metastases: a retrospective study.BMC surgery · 2025Article
- Socio-economic predictors and between-hospital variation in permanent stoma rates after segmental resection of colorectal cancer. A population-based register study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Article
- Quality of life outcomes in colorectal cancer survivors: insights from an observational study at a tertiary cancer center.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Observational
- Article
- Predictive factors associated with health-related quality of life in patients with colorectal cancer in Iran: a cross-sectional study.BMJ open · 2024Observational
- Article
- Do colorectal cancer patients with a postoperative stoma have sexual problems? A pooling up analysis of 2566 patients.International journal of colorectal disease · 2023Article
- Trends of colorectal cancer surgery in 2022.BJS open · 2023Article
- Health-related quality of life in rectal cancer: a topic more relevant now than ever.BJS open · 2022Article
Corrections and comments
- Commented on by
Authors and funding
26 authors.
Funding
Abstract
backgroundColorectal cancer management may require an ostomy formation; however, a stoma may negatively impact health-related quality of life (HRQoL). This study aimed to compare generic and stoma-specific HRQoL in patients with a permanent colostomy after rectal cancer across different countries.
methodA cross-sectional cohorts of patients with a colostomy after rectal cancer in Denmark, Sweden, Spain, the Netherlands, China, Portugal, Australia, Lithuania, Egypt, and Israel were invited to complete questionnaires regarding demographic and socioeconomic factors along with the Colostomy Impact (CI) score, European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30) and five anchor questions assessing colostomy impact on HRQoL. The background characteristics of the cohorts from each country were compared and generic HRQoL was measured with the EORTC QLQ-C30 presented for the total cohort. Results were compared with normative data of reference European populations. The predictors of reduced HRQoL were investigated by multivariable logistic regression, including demographic and socioeconomic factors and stoma-related problems.
resultsA total of 2557 patients were included. Response rates varied between 51-93 per cent. Mean time from stoma creation was 2.5-6.2 (range 1.1-39.2) years. A total of 25.8 per cent of patients reported that their colostomy impairs their HRQoL 'some'/'a lot'. This group had significantly unfavourable scores across all EORTC subscales compared with patients reporting 'no'/'a little' impaired HRQoL. Generic HRQoL differed significantly between countries, but resembled the HRQoL of reference populations. Multivariable logistic regression showed that stoma dysfunction, including high CI score (OR 3.32), financial burden from the stoma (OR 1.98), unemployment (OR 2.74), being single/widowed (OR 1.35) and young age (OR 1.01 per year) predicted reduced stoma-related HRQoL.
conclusionOverall HRQoL is preserved in patients with a colostomy after rectal cancer, but a quarter of the patients interviewed reported impaired HRQoL. Differences among several countries were reported and socioeconomic factors correlated with reduced quality of life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.