Evidence map›Paper›PMID 36545227›Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2022

Getting ahead of the game: in-hospital initiation of HFrEF therapies.

Jan Biegus, Yasbanoo Moayedi, Clara Saldarriaga, Piotr Ponikowski

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Harnessing the lymphatic system.Heart failure reviews · 2025
    Review
  9. High-intensity care for GDMT titration.Heart failure reviews · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Jan BiegusInstitute of Heart Diseases, Cardiology Department, Medical University, Borowska 213, 50-556 Wroclaw, Poland.ORCID https://orcid.org/0000-0001-9977-7722
Yasbanoo MoayediUniversity Health Network, Department of Medicine, Division of Cardiology, Ted Rogers Centre for Heart Function Research, Toronto, ON, M5G 2C2, Canada.
Clara SaldarriagaUniversity of Antioquia, CardioVID Clinic, Cardiology Department, 050021 Medellín, Colombia.
Piotr PonikowskiInstitute of Heart Diseases, Cardiology Department, Medical University, Borowska 213, 50-556 Wroclaw, Poland.
Wroclaw Medical University · PLUniversidad de Antioquia · COUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hospitalizations for heart failure (HF) have become a global problem worldwide. Each episode of HF decompensation may lead to deleterious short- and long- term consequences, but on the other hand is an unique opportunity to adjust the heart failure pharmacotherapy. Thus, in-hospital and an early post-discharge period comprise an optimal timing for initiation and optimization of the comprehensive management of HF. This timeframe affords clinicians an opportunity to up titrate and adjust guideline-directed medical therapies (GDMT) to potentially mitigate poor outcomes associated post-discharge and longer-term. This review will cover this timely concept, present the data of utilization of GDMT in HF populations, discuss recent evidence for in-hospital initiation and up-titration of GDMT with a need for post-discharge follow-up and implementation this into clinical practice in patients with heart failure and reduced ejection fraction.

Indexed as

Guideline directed medical therapyHeart failure therapyPharmacotherapyPrognosis

Identifiers

PMID36545227
PMCPMC9762886
OpenAlexW4312052646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.