Evidence map›Paper›PMID 36544971›Full record

ArticleLaryngoscope investigative otolaryngology2022

Virtual planning and 3D-printed guides for mandibular reconstruction: Factors impacting accuracy.

Donald J Annino, Rosh K Sethi, Elisabeth E Hansen, Sylvia Horne, Tanujit Dey, Eleni M Rettig, Ravindra Uppaluri, Jason I Kass, Laura A Goguen

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

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  6. [Study on influence of tooth-supported osteotomy guide plates on the accuracy of mandibular segmental resection and its surgical outcome].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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  7. Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation.Journal of biomedical materials research. Part B, Applied biomaterials · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Donald J AnninoDivision of Otolaryngology Brigham and Women's Hospital, Dana-Farber Cancer Institute Boston Massachusetts USA.
Rosh K SethiDivision of Otolaryngology Brigham and Women's Hospital, Dana-Farber Cancer Institute Boston Massachusetts USA.
Elisabeth E HansenHarvard Medical School Boston Massachusetts USA.
Sylvia HorneNorthwell Health New York New York USA.
Tanujit DeyCenter for Surgery and Public Health Brigham and Women's Hospital Boston Massachusetts USA.
Eleni M RettigDivision of Otolaryngology Brigham and Women's Hospital, Dana-Farber Cancer Institute Boston Massachusetts USA.
Ravindra UppaluriDivision of Otolaryngology Brigham and Women's Hospital, Dana-Farber Cancer Institute Boston Massachusetts USA.
Jason I KassReliant Medical Group Worcester Massachusetts USA.
Laura A GoguenDivision of Otolaryngology Brigham and Women's Hospital, Dana-Farber Cancer Institute Boston Massachusetts USA.
Brigham and Women's Hospital · USDana-Farber Brigham Cancer Center · USHarvard University · USNorthwell Health · USReliant Medical Group · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Examine accuracy and factors impacting accuracy for mandibular reconstruction with virtual surgical planning, 3D printed osteotomy guides and preoperatively bent mandibular reconstruction plate (VSP/3Dprinted-guide/plate). Method: Retrospective review of osseous-free-flap mandibular reconstructions with VSP/3Dprinted-guide/plate between January 2015 and July 2020 at a single academic medical center.Patient demographics, disease, and treatment variables were extracted. Accuracy was assessed by 3D-model-overlay with cephalometric and donor-bone segment length measurements. Multivariate analyses were performed to determine factors impacting cephalometric accuracy. Results: 60 cases met criteria: 41 (68%) cancer, 14 (23%) osteoradionecrosis (ORN), 5 (8%) secondary mandibular reconstruction. Thirteen cases (22%) were Brown class III or IV. Thirty-nine cases (65%) had ≥2 flap bone segments. Average donor-bone length was 82 mm (SD: 28). 3D-model-overlay accuracy demonstrated minimal deviation between planned and actual reconstruction: intercondylar distance = 2.10 mm (SD: 2.2); intergonial distance = 2.23 mm (SD: 1.9); anterior-posterior distance (APD) = 1.76 mm (SD: 1.5); gonial angle (GA) = 3.11 degrees (SD: 2.4). Mean change in donor-bone segment length inferiorly was 2.67 mm (SD: 2.6) and superiorly 3.27 mm (SD: 3.2). Higher number of donor-bone segments was associated with decreased accuracy in GA ( Conclusion: To our knowledge this is the largest series assessing surgical accuracy of VSP/3Dprinted-guide/plate for osseous-free-flap mandibular reconstruction. We demonstrate highly accurate results, with increased number of donor-bone segments and donor-bone length associated with decreased accuracy. Our findings further support VSP/3Dprinted-guide/plate as a reliable and accurate tool for mandibular reconstruction. Level of Evidence: Level 4.

Indexed as

3D printingcomputer aided designcomputer aided manufacturingcutting guidesfibula free flapmandibular reconstructionpre‐bent platevirtual surgical planning

Identifiers

PMID36544971
PMCPMC9764818
OpenAlexW4307159571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.