ArticleLaryngoscope investigative otolaryngology2022
Sinonasal IgG4-related sclerosing disease: A rare entity and challenging diagnosis.
Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Immunoglobulin G4-related Disease with Solitary Nasopharynx Involvement Mimicking Nasopharyngeal Tumor.Internal medicine (Tokyo, Japan) · 2026Article
- Immunoglobulin G4-related disease manifesting as a sino-orbital mass: a comprehensive case report and review of literature.AME case reports · 2026Article
- Sinonasal immunoglobulin G4-related disease: a case report of an atypical and rare entity.Journal of medical case reports · 2024Article
- Sinonasal schwannoma masquerading as an IgG4-related nasal mass.BMJ case reports · 2023Article
- Sinonasal IgG4-related sclerosing disease: A rare entity and challenging diagnosis.Laryngoscope investigative otolaryngology · 2022Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
Objectives: To describe the rare presentation, imaging and histological findings, and treatments in patients with IgG4-related disease (IgG4-RD) and diagnostic pitfalls and difficulties. Methods: Cases of sinonasal IgG4-RD were retrieved, and clinicopathological features were reviewed. Results: Seven cases of sinonasal IgG4-RD were identified over an 11-year period, including four males and three females, with an age range of 19-66 years (median 58 years). Patients presented with symptoms related to the mass effect of the lesions or the destructive nature of the disease including fullness, swelling, obstruction, and pain. Serum IgG and IgG4 levels, IgG/IgG4 ratios, storiform fibrosis, obliterative phlebitis, and plasma cell infiltration were seen in varying proportions. Bony erosion and tissue inflammation were present in some cases. Conclusion: Sinonasal IgG4-RD is exceedingly rare among other IgG4-RD and varied in its clinical presentation thus posing as a clinically difficult disease to diagnosis. Proper clinical, pathological, and immunohistopathological analysis is required for accurate diagnosis. Such disease should be considered in all cases of similar presentation to those in this study.Level of Evidence: 4.
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