Evidence map›Paper›PMID 36544927›Full record

ArticleLaryngoscope investigative otolaryngology2022

Persistence of lower vocal intensity in vocal fold paralysis with cricothyroid impairment after hyaluronate injection.

Kuo-Cheng Liu, Yi-An Lu, Hsiu-Feng Chuang, Li-Jen Hsin, Wan-Ni Lin, Alice M K Wong, Yu-Cheng Pei, Tuan-Jen Fang

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kuo-Cheng LiuDepartment of Physical Medicine and Rehabilitation New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation) New Taipei City Taiwan.
Yi-An LuDepartment of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan.
Hsiu-Feng ChuangDepartment of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan.
Li-Jen HsinDepartment of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan.
Wan-Ni LinDepartment of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan.
Alice M K WongDepartment of Physical Medicine and Rehabilitation Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan.ORCID https://orcid.org/0000-0003-3586-1292
Yu-Cheng PeiDepartment of Physical Medicine and Rehabilitation Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan.
Tuan-Jen FangDepartment of Otolaryngology Chang Gung Memorial Hospital at Linkou Taoyuan Taiwan.ORCID https://orcid.org/0000-0002-7805-3458
Chang Gung University · TWLinkou Chang Gung Memorial Hospital · TWChang Gung University of Science and Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Unilateral vocal fold paralysis (UVFP) affects the glottal gap, voice, and aerodynamics, whereas injection laryngoplasty (IL) using hyaluronate is an effective treatment for UVFP by decreasing the glottal gap to improve voice. Previous studies have shown that the involvement of cricothyroid (CT) muscle in UVFP patients further affects patients' aerodynamics, but it remains unclear whether the difference remains after IL. This study investigates whether the aerodynamic features observed in UVFP with CT involvement could still be observed after IL. Methods: This study recruited UVFP patients with dysphonia, and IL was performed within 6 months of initial symptoms. All subjects received assessments including videolaryngoscopy, voice analysis, and aerodynamics at three time points: before IL, 1 month after IL, and 6 months after IL. The glottal gap, voice, and aerodynamics between patients with and without CT involvement (the CT+ and CT- groups) were compared, and the change (Δ) before and after IL and repeated-measures analysis of variance (ANOVA) were also compared between the two groups. Result: A total of 71 patients with UVFP (22 in the CT+ group and 49 in the CT- group) were analyzed. After IL, the CT+ group showed a lower sound pressure level (SPL), higher Δair pressure, and smaller Δaerodynamic power than the CT- group. Conclusion: The CT+ group had a lower SPL, even after elevating air pressure to attempt to achieve a higher vocal intensity. The results suggest that although closure of the glottal gap was achieved by IL, the CT+ group still had a lower loudness and needed to sustain a higher peak air pressure when producing voice. Level of evidence: Level 4.

Indexed as

aerodynamicsair pressurecricothyroidinjection laryngoplastyunilateral vocal fold paralysis

Identifiers

PMID36544927
PMCPMC9764743
OpenAlexW4300960720

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.