Evidence map›Paper›PMID 36544643›Full record

ArticleAnnals of translational medicine2022

NLRP3 mediates trophoblastic inflammasome activation and protects against

Yu Gao, Min Zhou, Wen Zhang, Jinxing Jiang, Zhibin Ouyang, Yuanfang Zhu, Ning Li

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yu Gao *Obstetrics and Gynecology, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China.
Min Zhou *Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China.
Wen Zhang *Emergency Department, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China.
Jinxing JiangCytotherapy Laboratory, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China.
Zhibin OuyangCytotherapy Laboratory, The Second Clinical Medical College (Shenzhen People's Hospital), Jinan University, Shenzhen, China.
Yuanfang ZhuObstetrics and Gynecology, Shenzhen Bao'an Maternal and Child Health Hospital Affiliated to Jinan University, Jinan University, Shenzhen, China.
Ning LiBiotherapy Research Center, The Second Affiliated Hospital, School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Jinan University · CNFirst Affiliated Hospital of Jinan University · CNJilin University · CNShenzhen Third People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intrauterine Methods: A listeriosis murine model and cell culture system was used to investigate the role of trophoblastic nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 (NLRP3) in orchestrating innate immune responses to Results: Trophoblast cells constitutively expressed the components of the NLRP3 inflammasome. Conclusions: We conclude that trophoblast cells respond to

Indexed as

inflammasomeListeria monocytogenes (L. monocytogenes)nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 (NLRP3)Pregnancytrophoblast

Identifiers

PMID36544643
PMCPMC9761141
OpenAlexW4312114030

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.