Evidence map›Paper›PMID 36544433›Full record

ReviewBiotechnology and bioengineering2023

Prosthetic vascular grafts engineered to combat calcification: Progress and future directions.

Taylor K Brown, Sara Alharbi, Karen J Ho, Bin Jiang

Open access · hybridAbstract readReview
In one paragraph

Review in Biotechnology and bioengineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. [Research progress on calcification mechanism and anti-calcification strategies of vascular grafts].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Taylor K BrownDepartment of Biomedical Engineering, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0002-7673-0902
Sara AlharbiDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Karen J HoDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Bin JiangDepartment of Biomedical Engineering, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0003-2390-4312
Northwestern University · US

Funding

Regenerative Engineering Training Program (RE-Training)T32EB031527 · NIBIB · NORTHWESTERN UNIVERSITY · PI Guillermo Antonio Ameer · 2021 to 2026
$1.3M
NIBIB NIH HHS T32 EB031527
6 · The paper itself

Abstract

Calcification in prosthetic vascular conduits is a major challenge in cardiac and vascular surgery that compromises the long-term performance of these devices. Significant research efforts have been made to understand the etiology of calcification in the cardiovascular system and to combat calcification in various cardiovascular devices. Novel biomaterial design and tissue engineering strategies have shown promise in preventing or delaying calcification in prosthetic vascular grafts. In this review, we highlight recent advancements in the development of acellular prosthetic vascular grafts with preclinical success in attenuating calcification through advanced biomaterial design. We also discuss the mechanisms of action involved in the designs that will contribute to the further understanding of cardiovascular calcification. Lastly, recent insights into the etiology of vascular calcification will guide the design of future prosthetic vascular grafts with greater potential for translational success.

Indexed as

Blood Vessel ProsthesisTissue EngineeringBiocompatible MaterialsBiocompatible Materialsbiomaterial designcardiovascular diseasevascular calcificationvascular graft

Identifiers

PMID36544433
PMCPMC10023339
OpenAlexW4313236729

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.