Evidence map›Paper›PMID 36544200›Full record

ArticleJournal of orthopaedic surgery and research2022

Choosing the appropriate pharmacotherapy for nonspecific chronic low back pain.

Filippo Migliorini, Nicola Maffulli

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 10 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 10 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  3. Management of sacroiliac joint pain: current concepts.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Pooled it
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  5. Impact of education in patients undergoing physiotherapy for lower back pain: a level I systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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  10. Stem cells and discogenic back pain.British medical bulletin · 2023
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  14. Active and passive physical therapy in patients with chronic low-back pain: a level I Bayesian network meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 4 countries.

Filippo MiglioriniDepartment of Orthopedic, Trauma, and Reconstructive Surgery, University Clinic Aachen, RWTH Aachen University Clinic, 52064, Aachen, Germany. migliorini.md@gmail.com.ORCID http://orcid.org/0000-0001-7220-1221
Nicola MaffulliDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081, Baronissi, SA, Italy.
Orthopaedic Trauma Association · USUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmacological management of nonspecific chronic low back pain (NCLBP) aims to restore daily activities and improve the quality of life. No magic bullet exists for NCLBP; interventions to reduce pain and disability are available, but long-term results are unpredictable. Education in this regard needs to improve. This is often hard to accept for clinicians and patients, and provides a fertile soil to quacks, faith healers, and gurus to promote miraculous non-evidence-based solutions. The management of NCLBP is not well codified and extremely heterogeneous, and residual symptoms are common. Depending on the individual severity of NCLPB, pharmacological management may range from nonopioid to opioid analgesics. It is important to identify patients with generalized sensory hypersensitivity, who may benefit from a dedicated therapy. In this editorial, we provide an evidenced-based overview of the principles of pharmacological management of NCLPB.

Indexed as

Chronic PainLow Back PainAnalgesics, OpioidHumansPain MeasurementQuality of LifeAnalgesics, OpioidChronicLow back painPharmacological therapySpine

Identifiers

PMID36544200
PMCPMC9773490
OpenAlexW4312128769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.