Evidence map›Paper›PMID 36544141›Full record

ArticleEnvironmental health : a global access science source2022

Association between outdoor air pollution and chronic rhinosinusitis patient reported outcomes.

S Peeters, C Wang, E M Bijnens, D M A Bullens, W J Fokkens, C Bachert, P W Hellings, T S Nawrot, S F Seys

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Association between air pollution and allergic upper respiratory diseases: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Article
  3. Characterizing air pollution exposure methodologies in rhinology: a scoping review.International journal of environmental health research · 2025
    Article
  4. Article
  5. Article
  6. Understanding exposomes and its relation with cancer risk in Malaysia based on epidemiological evidence: a narrative review.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2024
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 5 countries.

S PeetersDepartment of Microbiology, Allergy and Clinical Immunology Research Group, Immunology & Transplantation, Herestraat 49/811, 3000, Louvain, KU, Belgium.
C WangCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
E M BijnensCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
D M A BullensDepartment of Microbiology, Allergy and Clinical Immunology Research Group, Immunology & Transplantation, Herestraat 49/811, 3000, Louvain, KU, Belgium.
W J FokkensDepartment of Otorhinolaryngology, Amsterdam University Medical Centres, Location AMC, Amsterdam, The Netherlands.
C BachertDepartment of Otorhinolaryngology, Upper Airways Research Laboratory, Ghent University, Ghent, Belgium.
P W HellingsDepartment of Microbiology, Allergy and Clinical Immunology Research Group, Immunology & Transplantation, Herestraat 49/811, 3000, Louvain, KU, Belgium.
T S NawrotCentre for Environmental Sciences, Hasselt University, Hasselt, Belgium.
S F SeysDepartment of Microbiology, Allergy and Clinical Immunology Research Group, Immunology & Transplantation, Herestraat 49/811, 3000, Louvain, KU, Belgium. sven.seys@kuleuven.be.
Ghent University · BEHasselt University · BEAmsterdam University Medical Centers · NLDepartment of Public Health · USKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aetiology of chronic rhinosinusitis (CRS) is multifactorial with a complex interplay between environmental, microbial endogenous and genetic factors. The impact of outdoor air pollution on prevalence or severity of CRS remains largely unknown.

methodsReal-life geolocation data (2017-2018, Belgium) from 278 CRS patients (2576 health records) using the mySinusitisCoach mobile application were analysed to calculate the patients' individual exposure to outdoor air pollutants (ozone (O

resultsThe adjusted seasonal model for the spring-summer (n = 1000 health entries, N = 83 patients) population revealed an increase of 6.07 (p < 0.0001) in overall CRS symptom scoring for an interquartile range (IQR) increase in exposure to O

conclusionExposure to outdoor air pollution is associated with increased symptom severity in CRS patients. The extent to which CRS patients are sensitive to outdoor air pollution exposure varies per season and depends on their sex and comorbid asthma status. mHealth technology has the potential to reveal novel insights on the patients' exposome and disease severity in the real-life situation.

Indexed as

Air PollutantsAir PollutionAsthmaChronic DiseaseEnvironmental ExposureFemaleHumansMaleNitrogen DioxideParticulate MatterAir PollutantsNitrogen DioxideParticulate MatterChronic rhinosinusitisOutdoor air pollutionPatient reported outcome measures

Identifiers

PMID36544141
PMCPMC9769041
OpenAlexW4312045026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.