Evidence map›Paper›PMID 36544057›Full record

ArticleLearning & behavior2023

Hippocampus and neocortex send and receive predictive information.

Eric A Thrailkill

Abstract readComment
In one paragraph

Article in Learning & behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Eric A ThrailkillVermont Center on Behavior and Health, Departments of Psychological Science and Psychiatry, University of Vermont, 2 Colchester Avenue, Room 106, Burlington, VT, 05405, USA. eric.thrailkill@uvm.edu.ORCID 0000-0003-2725-5428

Funding

Training in Translational Methods for Assessing Behavior Change and Relapse MechanismsK01DA044456 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI THRAILKILL, ERIC ALLEN · 2018 to 2022
$621k
NIDA NIH HHS K01 DA044456
6 · The paper itself

Abstract

A recent paper published in Nature by Yadav and colleagues (Nature 608 (7921): 153-160, 2022) illustrates a fundamental aspect on how different brain areas participate in memory storage and retrieval. After identifying neuron activity in the hippocampus CA1 region specific to multi-modal stimuli that predicted appetitive and aversive unconditioned stimuli (conjunctive stimulus encoding), the authors showed that neurons located in the anterior cingulate cortex dynamically encode the discrete sensory features of the outcome-predictive stimuli during training, and these highly specific feature-based projections can excite or inhibit conjunctive-coding neurons in the hippocampus during retrieval.

Indexed as

HippocampusNeocortexAnimalsGyrus CinguliNeurons

Identifiers

PMID36544057
PMCPMC10282101

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.