Evidence map›Paper›PMID 36543944›Full record

ArticleEye (London, England)2023

Effect of time to operative repair within twenty-four hours on visual acuity outcomes for open globe injuries.

Kevin G Makhoul, Racquel A Bitar, Grayson W Armstrong, Marguerite C Weinert, Alexander Ivanov, Francesca Kahale, Thong Ta, Alice C Lorch

Abstract read
In one paragraph

Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Overnight vs. daytime surgical repair in open globe injuries and their association with long-term visual outcomes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevin G MakhoulDepartment of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA. kevinmakhoul@gmail.com.
Racquel A BitarDepartment of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.
Grayson W ArmstrongDepartment of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.ORCID 0000-0001-9102-5868
Marguerite C WeinertDepartment of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.
Alexander IvanovDepartment of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.
Francesca KahaleDepartment of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.
Thong TaDepartment of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.ORCID 0000-0002-9538-083X
Alice C LorchDepartment of Ophthalmology, Massachusetts Eye and Ear, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeConvention is to perform open globe injury (OGI) repair within 24 h to minimize risk of endophthalmitis. However, there are limited data assessing how time to operative repair (OR) within 24 h impacts postoperative visual acuity (VA).

methodsManual retrospective chart review of 633 eyes at Massachusetts Eye and Ear (MEE) with a diagnosis of OGI between 2012 and 2022. Inclusion criteria were primary repair ≤ 24 h after injury and ≥1 month follow-up. Multivariate regression analysis was conducted with postoperative VA as primary outcome.

resultsOf the subjects, 489 (77.3%) were male and 496 (78.4%) were white. Demographics of OGI wounds included 320 (50.6%) rupture and 313 (49.4%) laceration; 126 (19.9%) with rAPD, 189 (29.9%) zone 3 injuries, 449 (71.2%) uveal prolapse, and 110 (17.4%) intraocular foreign body. Final postoperative LogMAR VAs consisted of 31% with a VA < 1.7, 9% with a VA of 1.9, 18% with a VA of 2.3, 27% with a VA of 2.7, and 11% with a VA of 3.0. Multivariate analysis showed no significant correlation between time to OR and postoperative VA (p = 0.800) [95%CI: -0.01,0.01]. Older age (p < 0.001) [95%CI: 0.00,0.01], worse presenting VA (p < 0.001) [95%CI: 0.17,0.32], rAPD (p < 0.001) [95%CI: 0.65,1.0], mechanism of rupture (p < 0.001) [95%CI: 0.19,0.54], higher zone of injury (p < 0.001) [95%CI: 0.25,0.45], and uveal prolapse (p = 0.003) [95%CI: 0.09,0.42] were significantly associated with worse final VA.

conclusionsTime to repair of OGIs within 24 h does not influence final VA. Optimization of surgical and patient factors may contribute more significantly to final VA than prioritizing more rapid time to OR.

Indexed as

Eye Injuries, PenetratingEyeFemaleHumansMalePrognosisRandom Amplified Polymorphic DNA TechniqueRetrospective StudiesVisual Acuity

Identifiers

PMID36543944
PMCPMC10366134

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.