Evidence map›Paper›PMID 36543814›Full record

ArticleScientific reports2022

Sex and menopause impact

Steven Jett, Jonathan P Dyke, Caroline Andy, Eva Schelbaum, Grace Jang, Camila Boneu Yepez, Silky Pahlajani, Ivan Diaz, Roberta Diaz Brinton, Lisa Mosconi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Systematic review ofFrontiers in aging neuroscience · 2023
    Pooled it
  5. Review
  6. Article
  7. Article
  8. Women's midlife: the front line of Alzheimer prevention.The Journal of clinical investigation · 2026
    Review
  9. Review
  10. Article
  11. Sex andInternational journal of molecular sciences · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. 17β-Estradiol Effects in Skeletal Muscle: ADiagnostics (Basel, Switzerland) · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Steven Jett *Department of Neurology, Weill Cornell Medicine, New York, NY, 10021, USA.
Jonathan P Dyke *Department of Radiology, Weill Cornell Medicine, New York, NY, USA.
Caroline AndyDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Eva SchelbaumDepartment of Neurology, Weill Cornell Medicine, New York, NY, 10021, USA.
Grace JangDepartment of Neurology, Weill Cornell Medicine, New York, NY, 10021, USA.
Camila Boneu YepezDepartment of Neurology, Weill Cornell Medicine, New York, NY, 10021, USA.
Silky PahlajaniDepartment of Neurology, Weill Cornell Medicine, New York, NY, 10021, USA.
Ivan DiazDepartment of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Roberta Diaz BrintonDepartment of Pharmacology, University of Arizona, Tucson, AZ, USA.
Lisa MosconiDepartment of Neurology, Weill Cornell Medicine, New York, NY, 10021, USA. lim2035@med.cornell.edu.
Weill Cornell Medicine · USCornell University · USUniversity of Arizona · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Timing of Menopausal Hormone Therapy across Perimenopause to Menopause Transition: Neuroimmune System in BrainP01AG026572 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Schantel Williams · 2006 to 2026
$53.7M
Sex Differences in the Molecular Determinants of Alzheimer's Disease Risk: Prodromal EndophenotypeR01AG057931 · NIA · UNIVERSITY OF ARIZONA · PI BRINTON, ROBERTA EILEEN, CHANG, RUI · 2018 to 2022
$6.0M
Modified Ketogenic Diet Effects on Alzheimer's Disease Biomarkers and Cognition in Mild Cognitive ImpairmentR01AG055122 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CRAFT, SUZANNE · 2017 to 2022
$5.2M
NCATS NIH HHS UL1 TR002384NIA NIH HHS P01 AG026572NIA NIH HHS R01 AG055122NIA NIH HHS R01 AG057931
6 · The paper itself

Abstract

Increasing evidence implicates sex and endocrine aging effects on brain bioenergetic aging in the greater lifetime risk of Alzheimer's disease (AD) in women. We conducted

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAdenosine TriphosphateBrainFemaleHumansMagnetic Resonance SpectroscopyMaleMenopauseOrganophosphatesPhosphocreatinePositron-Emission TomographySex CharacteristicsAdenosine TriphosphateAmyloid beta-PeptidesOrganophosphatesPhosphocreatine

Identifiers

PMID36543814
PMCPMC9772209
OpenAlexW4312045983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.