ArticleJournal of anatomy1987
Genesis of cilia and microvilli of rat nasal epithelia during prenatal development. III. Respiratory epithelium surface, including a comparison with the surface of the olfactory epithelium.
Article in Journal of anatomy, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 23 citations in OpenAlex.
- Design principles of ciliary signaling.Journal of cell science · 2025Review
- Potential Therapeutic Targets for Olfactory Dysfunction in Ciliopathies Beyond Single-Gene Replacement.Chemical senses · 2021Review
- Endogenous zinc nanoparticles in the rat olfactory epithelium are functionally significant.Scientific reports · 2020Article
- Immotile cilia syndrome in pigs. A model for human disease.The American journal of pathology · 1993Article
- A scanning electron microscopic study of the opossum nasal cavity prior to and shortly after birth.Anatomy and embryology · 1992Article
- Pre-natal development of rat nasal epithelia. IV. Freeze-fracturing on apices, microvilli and primary and secondary cilia of olfactory and respiratory epithelial cells, and on olfactory axons.Anatomy and embryology · 1988Article
- Pre-natal development of rat nasal epithelia. V. Freeze-fracturing on necklaces of primary and secondary cilia of olfactory and respiratory epithelial cells.Anatomy and embryology · 1988Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
During prenatal development the respiratory epithelium surface of the rat's nasal septum underwent the following changes. At intra-uterine day E14 there was a transformation from State I, cells with primary cilia only, to cells which also had microvilli (Stage II). Anterior parts of the nasal septum retained microvilli throughout further development. Posteriorly, centriole multiplication (Stage III) and formation of shafts of secondary cilia (Stage IV) occurred from around E16 and E18 onwards, respectively. From E18 to E20 numbers of cells with cilia increased at an overall rate of about 6 X 10(6) cells/cm2/day. Respiratory cilia and microvilli grew, on average, by about 0.3 micron/day and 0.1 micron/day, respectively. At Stage V, beginning around E19, the cilia became aligned within cells and, at Stage VI, beginning around E21, became synchronised between cells. Respiratory ciliogenesis in the nose is most precocious near the olfactory epithelium. The formation of respiratory cilia starts after that of olfactory cilia. However, unlike olfactory epithelium surfaces those of ciliated respiratory epithelia resembled those of adults around birth.
Indexed as
Identifiers
3654366PMC1261753W148869003What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.