Evidence map›Paper›PMID 36543538›Full record

ArticleeNeuro2023

Topographically Localized Modulation of Tectal Cell Spatial Tuning by Complex Natural Scenes.

Thomas T J Sainsbury, Giovanni Diana, Martin P Meyer

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Whole-brain imaging of freely-moving zebrafish.Frontiers in neuroscience · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Thomas T J SainsburyThe Centre for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorders, King's College London, London, United Kingdom, SE1 1UL thomas.sainsbury@kcl.ac.uk.
Giovanni DianaThe Centre for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorders, King's College London, London, United Kingdom, SE1 1UL.
Martin P MeyerThe Centre for Developmental Neurobiology and MRC Center for Neurodevelopmental Disorders, King's College London, London, United Kingdom, SE1 1UL.
King's College London · GBLundbeck Foundation · DK

Funding

Medical Research Council MR/N026063/1Medical Research Council MR/W006251/1Wellcome Trust 204788/Z/16/Z
6 · The paper itself

Abstract

The tuning properties of neurons in the visual system can be contextually modulated by the statistics of the area surrounding their receptive field (RF), particularly when the surround contains natural features. However, stimuli presented in specific egocentric locations may have greater behavioral relevance, raising the possibility that the extent of contextual modulation may vary with position in visual space. To explore this possibility, we utilized the small size and optical transparency of the larval zebrafish to describe the form and spatial arrangement of contextually modulated cells throughout an entire tectal hemisphere. We found that the spatial tuning of tectal neurons to a prey-like stimulus sharpens when the stimulus is presented against a background with the statistics of complex natural scenes, relative to a featureless background. These neurons are confined to a spatially restricted region of the tectum and have receptive fields centered within a region of visual space in which the presence of prey preferentially triggers hunting behavior. Our results suggest that contextual modulation of tectal neurons by complex backgrounds may facilitate prey-localization in cluttered visual environments.

Indexed as

Superior ColliculiZebrafishAnimalsNeuronsPhotic StimulationVision, Ocularcalcium imagingcontextual modulationdevelopmental biologynatural scenesvisionzebrafish

Identifiers

PMID36543538
PMCPMC9833049
OpenAlexW4312094992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.