Evidence map›Paper›PMID 36543531›Full record

ArticleJournal of medical ethics2023

Expanded terminal sedation in end-of-life care.

Laura Gilbertson, Julian Savulescu, Justin Oakley, Dominic Wilkinson

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical ethics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Laura GilbertsonFaculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
Julian SavulescuOxford Uehiro Centre for Practical Ethics, University of Oxford, Oxford, UK julian.savulescu@philosophy.ox.ac.uk.ORCID 0000-0003-1691-6403
Justin OakleyMonash Bioethics Centre, Monash University, Clayton, Victoria, Australia.
Dominic WilkinsonOxford Uehiro Centre for Practical Ethics, University of Oxford, Oxford, UK.ORCID 0000-0003-3958-8633
National University of Singapore · SGMonash University · AUUniversity of Oxford · GB

Funding

Wellcome Trust WT203132
6 · The paper itself

Abstract

Despite advances in palliative care, some patients still suffer significantly at the end of life. Terminal Sedation (TS) refers to the use of sedatives in dying patients until the point of death. The following limits are commonly applied: (1) symptoms should be refractory, (2) sedatives should be administered proportionally to symptoms and (3) the patient should be imminently dying. The term 'Expanded TS' (ETS) can be used to describe the use of sedation at the end of life outside one or more of these limits.In this paper, we explore and defend ETS, focusing on jurisdictions where assisted dying is lawful. We argue that ETS is morally permissible: (1) in cases of non-refractory suffering where earlier treatments are likely to fail, (2) where gradual sedation is likely to be ineffective or where unconsciousness is a clinically desirable outcome, (3) where the patient meets all criteria for assisted dying or (4) where the patient has greater than 2 weeks to live, is suffering intolerably, and sedation is considered to be the next best treatment option for their suffering.While remaining two distinct practices, there is scope for some convergence between the criteria for assisted dying and the criteria for ETS. Dying patients who are currently ineligible for TS, or even assisted dying, should not be left to suffer. ETS provides one means to bridge this gap.

Indexed as

EuthanasiaSuicide, AssistedTerminal CareDeathHumansHypnotics and SedativesPalliative CareHypnotics and SedativesEuthanasiaPain ManagementPalliative CareRight to DieTerminal Care

Identifiers

PMID36543531
PMCPMC10086483
OpenAlexW4312061423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.