Evidence map›Paper›PMID 36543213›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Bullous Pemphigoid in X-linked Alport Syndrome.

Masahiro Yamawaki, Kan Katayama, Mika Fujimoto, Hiroyuki Goto, Hiroto Yuasa, Yuji Kozuka, Mutsuki Mori, Daisuke Takahashi, Ryosuke Saiki, Yosuke Hirabayashi and 3 more

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In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Masahiro YamawakiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Kan KatayamaDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Mika FujimotoDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Hiroyuki GotoDepartment of Dermatology, Mie University Graduate School of Medicine, Japan.
Hiroto YuasaDepartment of Pathology, Mie University Hospital, Japan.
Yuji KozukaDepartment of Pathology, Mie University Hospital, Japan.
Mutsuki MoriDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Daisuke TakahashiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Ryosuke SaikiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Yosuke HirabayashiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Tomohiro MurataDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Keiichi YamanakaDepartment of Dermatology, Mie University Graduate School of Medicine, Japan.
Kaoru DohiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.
Mie University · JPMie University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin lesions in X-linked Alport syndrome (XLAS) are rarely observed. Bullous pemphigoid (BP) is caused by autoantibodies against BP180, also called α1 (XVII) chain, in the basement membrane zone (BMZ). A 48-year-old man with XLAS developed tense blisters. A skin biopsy showed a cleft between the basal cell layer and dermis, with the infiltration of neutrophils and eosinophils. α1 (XVII) staining was positive on the epidermal side of α2/5 (IV) staining. Oral prednisolone improved his symptoms gradually. Abundant tense blisters on the palms and soles might suggest an important role of the α5 (IV) chain in the integrity of BMZ.

Indexed as

Nephritis, HereditaryPemphigoid, BullousBlisterCollagen Type IVHumansMaleMiddle AgedCOL4A5 protein, humanCollagen Type IVbasement membrane zonebullous pemphigoidCOL4A5X-linked Alport syndrome

Identifiers

PMID36543213
PMCPMC10484771
OpenAlexW4312094015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.