Evidence map›Paper›PMID 36543140›Full record

ArticleCell reports2022

Global insights into the fine tuning of human A

Guillaume Ferré, Kara Anazia, Larissa O Silva, Naveen Thakur, Arka P Ray, Matthew T Eddy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Single-molecule visualization of human ACommunications biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Guillaume FerréDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Kara AnaziaDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Larissa O SilvaDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Naveen ThakurDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Arka P RayDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Matthew T EddyDepartment of Chemistry, University of Florida, Gainesville, FL 32611, USA. Electronic address: matthew.eddy@chem.ufl.edu.
University of Florida · US

Funding

R35 Supplement - Equipment SupplementR35GM138291 · NIGMS · UNIVERSITY OF FLORIDA · PI Matthew Thomas Eddy · 2020 to 2026
$2.5M
Chemistry-Biology Interface Training Program at the University of FloridaT32GM136583 · NIGMS · UNIVERSITY OF FLORIDA · PI Chenglong Li · 2020 to 2026
$1.1M
NIGMS NIH HHS R35 GM138291NIGMS NIH HHS T32 GM136583
6 · The paper itself

Abstract

G protein-coupled receptor (GPCR) conformational plasticity enables formation of ternary signaling complexes with intracellular proteins in response to binding extracellular ligands. We investigate the dynamic process of GPCR complex formation in solution with the human A

Indexed as

GTP-Binding ProteinsReceptors, G-Protein-CoupledHumansLigandsMagnetic Resonance SpectroscopyMolecular ConformationProtein ConformationReceptor, Adenosine A2ASignal TransductionGTP-Binding ProteinsLigandsReceptor, Adenosine A2AReceptors, G-Protein-CoupledA(2A) adenosine receptorbiophysicsCP: Molecular biologyGPCRG(s) proteinmini-G(s)NMRsignaling complexes

Identifiers

PMID36543140
PMCPMC9832913
OpenAlexW4312084847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.