Evidence map›Paper›PMID 36543132›Full record

ArticleCell reports2022

Kir4.2 mediates proximal potassium effects on glutaminase activity and kidney injury.

Andrew S Terker, Yahua Zhang, Juan Pablo Arroyo, Shirong Cao, Suwan Wang, Xiaofeng Fan, Jerod S Denton, Ming-Zhi Zhang, Raymond C Harris

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Potassium and the kidney.Nature reviews. Nephrology · 2026
    Review
  3. Article
  4. How Does Dietary Potassium Influence BP?Journal of the American Society of Nephrology : JASN · 2026
    Review
  5. Review
  6. Alteration in tissue electrolyte and water balance in pregnant mice: the importance of potassium.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  7. KiScience · 2025
    Article
  8. Article
  9. Article
  10. Roles of calcium in ameloblasts during tooth development: A scoping review.Journal of Taibah University Medical Sciences · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Macrophage SPAK deletion limits a low potassium-induced kidney inflammatory program.American journal of physiology. Renal physiology · 2024
    Article
  16. Article
  17. Chronic kidney disease increases the susceptibility to negative effects of low and high potassium intake.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andrew S TerkerDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, S-3206 MCN 1161 21st Ave South, Nashville, TN 37232, USA; Vanderbilt Center for Kidney Disease, Nashville, TN, USA. Electronic address: andrew.s.terker@vumc.org.
Yahua ZhangDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, S-3206 MCN 1161 21st Ave South, Nashville, TN 37232, USA; Vanderbilt Center for Kidney Disease, Nashville, TN, USA.
Juan Pablo ArroyoDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, S-3206 MCN 1161 21st Ave South, Nashville, TN 37232, USA; Vanderbilt Center for Kidney Disease, Nashville, TN, USA.
Shirong CaoDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, S-3206 MCN 1161 21st Ave South, Nashville, TN 37232, USA; Vanderbilt Center for Kidney Disease, Nashville, TN, USA.
Suwan WangDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, S-3206 MCN 1161 21st Ave South, Nashville, TN 37232, USA; Vanderbilt Center for Kidney Disease, Nashville, TN, USA.
Xiaofeng FanDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, S-3206 MCN 1161 21st Ave South, Nashville, TN 37232, USA; Vanderbilt Center for Kidney Disease, Nashville, TN, USA.
Jerod S DentonDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.
Ming-Zhi ZhangDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, S-3206 MCN 1161 21st Ave South, Nashville, TN 37232, USA; Vanderbilt Center for Kidney Disease, Nashville, TN, USA. Electronic address: ming-zhi.zhang@vumc.org.
Raymond C HarrisDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center, S-3206 MCN 1161 21st Ave South, Nashville, TN 37232, USA; Vanderbilt Center for Kidney Disease, Nashville, TN, USA; Department of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, USA. Electronic address: ray.harris@vumc.org.
Vanderbilt University Medical Center · USVanderbilt University · US

Funding

Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
The Role of the EGF Receptor in Acute and Chronic Renal InjuryR01DK051265 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RAYMOND C. HARRIS, Mingzhi Zhang · 1997 to 2026
$10.1M
The role of the innate immune cell cyclooxygenase/prostaglandin system in blood pressureregulationR01DK062794 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RAYMOND C. HARRIS, Mingzhi Zhang · 2003 to 2026
$9.4M
The Role of renal macrophages in recovery from renal injuryR01DK095785 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RAYMOND C. HARRIS, Mingzhi Zhang · 2013 to 2026
$6.7M
Vanderbilt O'Brien Kidney Center - Core D - Clinical and Translational CoreP30DK114809 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILSON, MATTHEW H · 2017 to 2021
$5.9M
VANDERBILT NEPHROLOGY TRAINING PROGRAMT32DK007569 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARRIS, RAYMOND C., IKIZLER, TALAT ALP · 1988 to 2024
$5.8M
Innovative therapeutic approaches to treat chronic kidney diseaseDP5OD033412 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TERKER, ANDREW S. · 2022 to 2025
$2.2M
NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK114809NIDDK NIH HHS R01 DK051265NIDDK NIH HHS R01 DK062794NIDDK NIH HHS R01 DK095785NIDDK NIH HHS T32 DK007569NIH HHS DP5 OD033412
6 · The paper itself

Abstract

Inadequate potassium (K

Indexed as

PotassiumPotassium Channels, Inwardly RectifyingGlutaminaseKidneyNephronsGlutaminasePotassiumPotassium Channels, Inwardly RectifyingaldosteroneammoniagenesisCP: Metabolismglutaminasekidney injuryKir4.2potassiumproximal tubule

Identifiers

PMID36543132
PMCPMC9827473
OpenAlexW4312084867

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.