Evidence map›Paper›PMID 36543101›Full record

ArticleCell reports. Medicine2022

New use for an old drug: Metformin and atrial fibrillation.

Manlio Vinciguerra, Ivan Olier, Sandra Ortega-Martorell, Gregory Y H Lip

Registry-linked trialOpen access · goldAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports. Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05878535 (The Efficacy And Safety Of Metformin For The Treatment Of Atrial Fibrillation), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05878535 phase2unknown statusnot on this mapstarted 2024, after this paper: background citation

The Efficacy And Safety Of Metformin For The Treatment Of Atrial Fibrillation

TypeinterventionalSponsorArab Contractors Medical CentreRan2024 to 2025Enrolled770ConditionsAtrial FibrillationArmsMetformin, Placebo
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Manlio VinciguerraLiverpool Centre for Cardiovascular Science (LCCS) at University of Liverpool, Liverpool Heart and Chest Hospital, Liverpool John Moores University, Liverpool, UK; Faculty of Health, Liverpool John Moores University, Liverpool, UK.
Ivan OlierLiverpool Centre for Cardiovascular Science (LCCS) at University of Liverpool, Liverpool Heart and Chest Hospital, Liverpool John Moores University, Liverpool, UK; School of Computer Science and Mathematics, Liverpool John Moores University, Liverpool, UK.
Sandra Ortega-MartorellLiverpool Centre for Cardiovascular Science (LCCS) at University of Liverpool, Liverpool Heart and Chest Hospital, Liverpool John Moores University, Liverpool, UK; School of Computer Science and Mathematics, Liverpool John Moores University, Liverpool, UK.
Gregory Y H LipLiverpool Centre for Cardiovascular Science (LCCS) at University of Liverpool, Liverpool Heart and Chest Hospital, Liverpool John Moores University, Liverpool, UK; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. Electronic address: gregory.lip@liverpool.ac.uk.
Aalborg University · DKLiverpool Heart and Chest Hospital · GBLiverpool John Moores University · GBUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lal and colleagues

Indexed as

Atrial FibrillationDiabetes Mellitus, Type 2MetforminHumansMetformin

Identifiers

PMID36543101
PMCPMC9798075
OpenAlexW4312082555

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.