ArticlePLoS neglected tropical diseases2022
Extensive diversity of RNA viruses in ticks revealed by metagenomics in northeastern China.
Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Global epidemiology of tick-borneFrontiers in cellular and infection microbiology · 2026Pooled it
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- Genomic Characterization of a Novel Victorivirus Detected in a Sample Derived From a Human-Biting Tick in Japan.Microbiology and immunology · 2026Article
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- Rattus norvegicus and Rattus tanezumi as hub hosts for viral diversity and potential spillover on Hainan Island, China.NPJ biofilms and microbiomes · 2026Article
- The risk of pathogenic tick-borne viruses in Northeast Asia: a genomic and ecological modelling study.Science China. Life sciences · 2026Article
- Discovery of a novel coltivirus in a newly identified Bat Bug Species (Heteroptera: Cimicidae) in Cambodia.PLoS neglected tropical diseases · 2026Article
- High throughput sequencing in the diagnosis and surveillance of tick-borne diseases: A narrative review.One health (Amsterdam, Netherlands) · 2026Review
- Human 3D liver spheroids support productive infection of a novel tick-borne phenuivirus.One health (Amsterdam, Netherlands) · 2026Article
- Alongshan virus in the virome of Ixodes hexagonus ticks in the United Kingdom.Ticks and tick-borne diseases · 2026Article
- Metaviromic analysis of Ixodes ticks in Northwestern Russia reveals high viral diversity and novel RNA virus lineages.Scientific reports · 2026Article
- Development and evaluation of single-plex TaqMan real-time quantitative PCR assays for the detection of six tick-borne pathogenic viruses in northeastern China.Frontiers in cellular and infection microbiology · 2026Article
- Article
- Evaluation of the vector competence ofFrontiers in cellular and infection microbiology · 2026Article
- Virome Diversity and Zoonotic Risks of Haemaphysalis concinna Ticks in Northeastern China.Transboundary and emerging diseases · 2026Article
- Identification of a novel pegivirus in reindeer (Rangifer tarandus valentinae) in Northeastern China.BMC veterinary research · 2025Article
- RNA virome of ticks and fleas infesting Marmota himalayana from the Qinghai-Tibet plateau.Animal microbiome · 2025Article
- Metagenomic next-generation sequencing identifies tick-carried pathogens on Tarim Red Deer in Southern Xinjiang.Open veterinary journal · 2025Article
- Structural Features of Nucleoproteins from the Recently DiscoveredInternational journal of molecular sciences · 2025Article
- Molecular evolution and spatial transmission of Dabieshan tick virus in Jilin Province, northeastern China.iScience · 2025Article
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Authors and funding
17 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTicks act as important vectors of infectious agents, and several emerging tick-borne viruses have recently been identified to be associated with human diseases in northeastern China. However, little is known about the tick virome in northeastern China.
methodsTicks collected from April 2020 to July 2021 were pooled for metagenomic analysis to investigate the virome diversity in northeastern China.
resultsIn total, 22 RNA viruses were identified, including four each in the Nairoviridae and Phenuiviridae families, three each in the Flaviviridae, Rhabdoviridae, and Solemoviridae families, two in the Chuviridae family, and one each in the Partitiviridae, Tombusviridae families and an unclassified virus. Of these, eight viruses were of novel species, belonging to the Nairoviridae (Ji'an nairovirus and Yichun nairovirus), Phenuiviridae (Mudanjiang phlebovirus), Rhabdoviridae (Tahe rhabdovirus 1-3), Chuviridae (Yichun mivirus), and Tombusviridae (Yichun tombus-like virus) families, and five members were established human pathogens, including Alongshan virus, tick-borne encephalitis virus, Songling virus, Beiji nairovirus, and Nuomin virus. I. persulcatus ticks had significant higher number of viral species than H. japonica, H. concinna, and D. silvarum ticks. Significant differences in tick viromes were observed among Daxing'an, Xiaoxing'an and Changbai mountains.
conclusionsThese findings showed an extensive diversity of RNA viruses in ticks in northeastern China, revealing potential public health threats from the emerging tick-borne viruses. Further studies are needed to explain the natural circulation and pathogenicity of these viruses.
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