ArticlePloS one2022
HIV incidence and associated risk factors in adolescent girls and young women in South Africa: A population-based cohort study.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 42 citations in OpenAlex.
- Higher Acceptability of the Monthly Dapivirine Ring Versus Daily Oral Pre-Exposure Prophylaxis Among Adolescent Girls and Young Women in Sub-Saharan Africa in the REACH Trial.Journal of acquired immune deficiency syndromes (1999) · 2025Trial
- Decision-making and acceptability of subcutaneously administered broadly neutralising monoclonal antibodies for HIV prevention amongst CAPRISA 012A trial participants in Durban, South Africa.Scientific reports · 2025Trial
- From Intervention to Practice: HIV Anti-Stigma Empowerment Readiness Among Service Providers in Canada.Journal of racial and ethnic health disparities · 2026Article
- Structural determinants of HIV inequities in South Africa: Policy analysis of the national strategic plan for HIV 2023-2028.Health policy OPEN · 2026Article
- Article
- Well-care visit attendance among children of adolescent mothers in South Africa: a theory-informed mixed-methods study.BMC public health · 2026Article
- Patterns of Sexual Behaviors and Sexual Partner Characteristics as Predictors of Perceived HIV Risk and HIV Status Among Adolescent Girls and Young Women in Kenya.AIDS and behavior · 2026Article
- A conceptual framework for integrating HIV, STIs and pregnancy prevention services in Vhembe District, Limpopo, South Africa: improving teenagers' health outcomes.BMC public health · 2026Article
- A qualitative study assessing the acceptability of a multi-agent AI Chatbot for providing HIV and mental health support among men who have sex with men and transgender women in KwaZulu-Natal, South Africa.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2026Article
- HIV incidence among sexually active young males and females in Kisumu County, Western Kenya.PloS one · 2026Article
- Development and Validation of an Integrated HIV/STI, and Pregnancy Prevention Programme: Improving Adolescent Sexual Health Outcomes.Tropical medicine and infectious disease · 2025Article
- Experiences of adolescent girls and young women of oral PrEP uptake in rural KwaZulu-Natal.African journal of primary health care & family medicine · 2025Article
- Profiling HIV Risk and Determined, Resilient, Empowered AIDS-Free, Mentored, and Safe (DREAMS) Program Reach Among Adolescent Girls and Young Women (AGYW) in Namibia: Secondary Analysis of Population and Program Data.Tropical medicine and infectious disease · 2025Article
- Article
- Mobile Health Intervention Tools Promoting HIV Pre-Exposure Prophylaxis Among Adolescent Girls and Young Women in Sub-Saharan Africa: Scoping Review.JMIR mHealth and uHealth · 2025Article
- Tackling the Triple Threat in Kenya: Factors Associated with Protection against HIV Risk, Gender-Based Violence, and Pregnancy among Adolescent Girls and Young Women.AIDS and behavior · 2025Article
- Differences in HIV risk factors between South African adolescents and adult women and their association with sexually transmitted infections.Sexually transmitted infections · 2025Observational
- HIV Vulnerability Typologies Among Adolescent Girls and Young Women in Lesotho: A Population-Based, Cross-Sectional, Latent Class Analysis.The Journal of the Association of Nurses in AIDS Care : JANAC · 2025Article
- Talking about PrEP: South African adolescent girls and young women's communication about pre-exposure prophylaxis with partners, parents and peers.Frontiers in reproductive health · 2025Article
- The contribution of PrEP programmes to triple elimination efforts: a cross-sectional study of status and opportunities.Frontiers in reproductive health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundIn sub-Saharan Africa, high HIV incidence rates in adolescent girls and young women (AGYW) persist despite extensive HIV prevention efforts.
methodsA prospective cohort of 2,710 HIV-negative AGYW (15-24 years) in KwaZulu-Natal, South Africa were interviewed at baseline and followed-up approximately 18 months later (2014-2017). Associations between HIV seroconversion and socio-demographic and behavioural variables measured at baseline and follow-up were examined using Cox regression and a proximate determinants framework. Inter-relationships between determinants were measured using logistic regression. Separate models were built for 15-19 and 20-24-year-olds.
resultsWeighted HIV incidence was 3.92 per 100 person-years (95% confidence interval: 3.27-4.69; 163 seroconversions over 4,016 person-years). Among 15-19-year-olds, absence of family support (adjusted hazards ratio (aHR): 3.82 (1.89-7.72)), having a circumcised partner (aHR: 0.5 (0.27-0.94)) or one who was HIV-positive and not on antiretroviral therapy (ART) (aHR: 6.21 (2.56-15.06)) were associated with HIV incidence. Those reporting an absence of family support were also more likely to report >1 partner during follow-up (odds ratio (OR): 2.7(1.11-6.57)). Among 20-24-year-olds, failure to complete secondary school (aHR: 1.89 (1.11-3.21)), inconsistent condom use (aHR: 3.01 (1.14-7.96)) and reporting partner(s) who were HIV-positive and not on ART (aHR: 7.75 (3.06-19.66)) were associated with HIV incidence. Failure to complete secondary school among 20-24-year-olds was associated with inconsistent condom use (OR: 1.82 (1.20-2.77)) and reporting an HIV-positive partner not on ART (OR: 3.53(1.59-7.82)) or an uncircumcised partner (OR: 1.39 (1.08-1.82).
conclusionAbsence of family support and incomplete schooling are associated with risky sexual behaviours and HIV acquisition in AGYW. In addition, partner-level prevention-condom use, medical circumcision, and viral suppression-continue to play an important role in reducing HIV risk in AGYW. These findings support the use of combination HIV prevention programs that consider structural as well as biological and behavioural HIV risk factors in their design.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.