ArticlePlant physiology2023
The MYB59 transcription factor negatively regulates salicylic acid- and jasmonic acid-mediated leaf senescence.
Article in Plant physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
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23 citing papers in PubMed, 37 citations in OpenAlex.
- MYB59 is Linked to Natural Variation of Water-Use Associated With Warmer Temperatures inPlant-environment interactions (Hoboken, N.J.) · 2026Article
- Natural variation in OsMYB305 downregulating cytokinin-mediated inhibition of leaf senescence contributes to regional adaptation in rice.The New phytologist · 2026Article
- Nitrogen Status Rewires Transcriptional Regulation of Dhurrin, a Dual-Purpose Defense Metabolite inPlant direct · 2026Article
- Correlative Changes in Endogenous Polyamines and Hormones Associated with Aging in AncientPlants (Basel, Switzerland) · 2026Article
- Regulatory Network of Leaf Senescence inInternational journal of molecular sciences · 2026Review
- DIVARICATA1 Promotes Leaf Degreening and Senescence in Arabidopsis.Plants (Basel, Switzerland) · 2026Article
- Expression profiles of transcription factors and aquaporins suggest putative roles in rubber biosynthesis regulation and drought stress adaptation in guayule.Scientific reports · 2026Article
- Application of quercetin enhances tobacco resistance to Phytophthora nicotianae.Functional & integrative genomics · 2025Article
- The Module WmABF1-1-WmMYB111 Manipulates the Leaf Senescence of Welwitschia by Integrative Regulation of Abscisic Acid Biosynthesis, Chlorophyll Degradation and Nitrogen Transportation.Plant biotechnology journal · 2025Article
- Transcription Factor BnaC04.MYB89 Negatively Regulates Seed Fatty Acid Biosynthesis inPlants (Basel, Switzerland) · 2025Article
- Comprehensive Identification of Key Genes Responsible for Leaf Senescence of Rice (Plants (Basel, Switzerland) · 2025Article
- Salicylic acid accumulation: emerging molecular players and novel perspectives on plant development and nutrition.Journal of experimental botany · 2025Review
- Advances in the study of senescence mechanisms in the genusHorticulture research · 2025Article
- Article
- Identification and functional characterization of the MYB transcription factorFrontiers in plant science · 2025Article
- Comprehensive Analysis ofInternational journal of molecular sciences · 2024Article
- Arabidopsis apoplast TET8 positively correlates to leaf senescence, andPlant direct · 2024Article
- Integrated transcriptomic and proteomic analysis of exogenous abscisic acid regulation on tuberous root development inFrontiers in nutrition · 2024Article
- The Chemical Composition and Transcriptome Analysis Reveal the Mechanism of Color Formation in Tea (International journal of molecular sciences · 2023Article
- Transcriptomic Analysis of Three Differentially Senescing Maize (International journal of molecular sciences · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leaf senescence is the final stage of leaf development and is affected by various exogenous and endogenous factors. Transcriptional regulation is essential for leaf senescence, however, the underlying molecular mechanisms remain largely unclear. In this study, we report that the transcription factor MYB59, which was predominantly expressed in early senescent rosette leaves, negatively regulates leaf senescence in Arabidopsis (Arabidopsis thaliana). RNA sequencing revealed a large number of differentially expressed genes involved in several senescence-related biological processes in myb59-1 rosette leaves. Chromatin immunoprecipitation and transient dual-luciferase reporter assays demonstrated that MYB59 directly repressed the expression of SENESCENCE ASSOCIATED GENE 18 and indirectly inhibited the expression of several other senescence-associated genes to delay leaf senescence. Moreover, MYB59 was induced by salicylic acid (SA) and jasmonic acid (JA). MYB59 inhibited SA production by directly repressing the expression of ISOCHORISMATE SYNTHASE 1 and PHENYLALANINE AMMONIA-LYASE 2 and restrained JA biosynthesis by directly suppressing the expression of LIPOXYGENASE 2, thus forming two negative feedback regulatory loops with SA and JA and ultimately delaying leaf senescence. These results help us understand the novel function of MYB59 and provide insights into the regulatory network controlling leaf senescence in Arabidopsis.
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