Evidence map›Paper›PMID 36542486›Full record

ArticleMolecular biology of the cell2023

An approach for quantitative mapping of synaptic periactive zone architecture and organization.

Steven J Del Signore, Margalit G Mitzner, Anne M Silveira, Thomas G Fai, Avital A Rodal

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Steven J Del SignoreDepartment of Biology, Brandeis University, Waltham, MA 02453.ORCID 0000-0001-6007-9732
Margalit G MitznerDepartment of Biology, Brandeis University, Waltham, MA 02453.
Anne M SilveiraDepartment of Biology, Brandeis University, Waltham, MA 02453.
Thomas G FaiDepartment of Mathematics, Brandeis University, Waltham, MA 02453.
Avital A RodalDepartment of Biology, Brandeis University, Waltham, MA 02453.ORCID 0000-0002-2051-8304
Brandeis University · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Predoctoral Training in Cross-Disciplinary Molecular and Cellular BiologyT32GM139798 · NIGMS · BRANDEIS UNIVERSITY · PI Paul Garrity, Bruce L Goode · 2021 to 2026
$3.5M
Organization and Function of the Periactive ZoneR01NS116375 · NINDS · BRANDEIS UNIVERSITY · PI Avital Adah Rodal · 2020 to 2026
$2.5M
NIGMS NIH HHS T32 GM139798NIH HHS P40 OD018537NINDS NIH HHS R01 NS116375
6 · The paper itself

Abstract

Following exocytosis at active zones, synaptic vesicle membranes and membrane-bound proteins must be recycled. The endocytic machinery that drives this recycling accumulates in the periactive zone (PAZ), a region of the synapse adjacent to active zones, but the organization of this machinery within the PAZ, and how PAZ composition relates to active zone release properties, remains unknown. The PAZ is also enriched for cell adhesion proteins, but their function at these sites is poorly understood. Here, using Airyscan and stimulated emission depletion imaging of

Indexed as

Drosophila ProteinsSynapsesAnimalsDrosophilaMembrane ProteinsSynaptic TransmissionSynaptic VesiclesDrosophila ProteinsMembrane Proteins

Identifiers

PMID36542486
PMCPMC10208105
OpenAlexW4312064873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.