SynthesisArquivos brasileiros de cardiologia2022
Hospital Mortality from Myocardial Infarction in Latin America and the Caribbean: Systematic Review and Meta-Analysis.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of acute kidney injury in Mexico; a systematic review and meta-analysis of pre-pandemic reports.Renal failure · 2025Pooled it
- Pooled it
- Identification of biomarkers associated with mitochondria and macrophage polarization in acute myocardial infarction: a bioinformatics analysis and validation study.Journal of cardiothoracic surgery · 2026Article
- Factors that impact in-hospital mortality due to STEMI versus NSTEMI in a first percutaneous coronary intervention: survival analysis.Archivos de cardiologia de Mexico · 2026Article
- Platelet Membrane and miR-181a-5p Doubly Optimized Nanovesicles Enhance Cardiac Repair Post-Myocardial Infarction through Macrophage Polarization.ACS applied materials & interfaces · 2025Article
- Copper homeostasis and cuproptosis in myocardial infarction: molecular mechanisms, treatment strategies and potential therapeutic targets.Frontiers in pharmacology · 2025Review
- Characteristics and risk factors for mortality in patients with acute coronary syndrome concomitant sepsis: a retrospective multicenter cohort study.Frontiers in cardiovascular medicine · 2025Article
- Nonlinear relationship between blood urea nitrogen to albumin ratio and in-hospital mortality in non-diabetic patients with non-ST-segment elevation myocardial infarction.Frontiers in nutrition · 2025Article
- Article
- Trends in primary percutaneous coronary intervention for the treatment of acute coronary ST-elevation myocardial infarction in Latin American countries: insights from the CECI consortium.Frontiers in cardiovascular medicine · 2024Article
- Clinical registries in Acute Myocardial Infarction.Arquivos brasileiros de cardiologia · 2023Article
- High Mortality for Myocardial Infarction in Latin America and the Caribbean: Making the Case for Systems of Care Implementation in Brazil.Arquivos brasileiros de cardiologia · 2022Article
- Predictive Value of D-Dimer for In-Hospital Mortality in Non-Diabetic Patients with Non-ST-segment Elevation Myocardial Infarction.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Development and Validation of a Nomogram Model for Predicting in-Hospital Mortality in non-Diabetic Patients with non-ST-Segment Elevation Acute Myocardial Infarction.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMost cardiovascular deaths occur in low- and middle-income countries and myocardial infarction is one of the main life-threatening conditions.
objectiveWe assessed all-cause in-hospital mortality in patients admitted for myocardial infarction (STEMI and NSTEMI) in Latin America and the Caribbean from 2000 onward.
methodsWe systematically searched in electronic bibliographic databases for cohort studies which reported in-hospital mortality due to STEMI and NSTEMI. A meta-analysis was performed and a p-value < 0.05 was considered significant.
resultsWe identified 38 studies (29 STEMI, 3 NSTEMI and 6 both). Pooled STEMI in-hospital mortality was 9.9% (95% CI: 9.1 - 10.7). Heterogeneity was not trivial (I2 = 74% and prediction interval = 6.6 - 14.5). The percentage of reperfusion therapy and decade explain part of the heterogeneity (I2 = 54%). The higher the rate of reperfusion therapy, the lower the in-hospital mortality (coefficient = -0.009, 95% CI: -0.013 to -0.006, p<0.001). This mortality was higher in the first decade as compared with the second (coefficient = -0.14, 95% CI: -0.27 to -0.02, p=0.047). Pooled NSTEMI in-hospital mortality was 6.3% (95% CI: 5.4 - 7.4) and heterogeneity was null.
conclusionPooled STEMI in-hospital mortality in low- and middle-income countries was high in comparison with rates reported in high income countries. To improve these estimates, higher use of reperfusion therapy must be pursued. Pooled NSTEMI in-hospital mortality was similar to the ones found in high-income countries; however, it was based on few studies and most of them were carried out in two countries.
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