ArticleACS synthetic biology2023
Encoding, Decoding, and Rendering Information in DNA Nanoswitch Libraries.
Article in ACS synthetic biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- [Binary encryption comprehensive experiment based on agarose gel electrophoresis].Se pu = Chinese journal of chromatography · 2026Article
- Mismatch-Induced Toehold-Free Strand Displacement Used to Control a DNA Nanodevice.ACS synthetic biology · 2025Article
- Isothermal assembly of DNA nanostructures.Chemical communications (Cambridge, England) · 2025Review
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Authors and funding
3 authors.
Funding
Abstract
DNA-based construction allows the creation of molecular devices that are useful in information storage and processing. Here, we combine the programmability of DNA nanoswitches and stimuli-responsive conformational changes to demonstrate information encoding and graphical readout using gel electrophoresis. We encoded information as 5-bit binary codes for alphanumeric characters using a combination of DNA and RNA inputs that can be decoded using molecular stimuli such as a ribonuclease. We also show that a similar strategy can be used for graphical visual readout of alphabets on an agarose gel, information that is encoded by nucleic acids and decoded by a ribonuclease. Our method of information encoding and processing could be combined with DNA actuation for molecular computation and diagnostics that require a nonarbitrary visual readout.
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