Evidence map›Paper›PMID 36541767›Full record

ArticleAntimicrobial agents and chemotherapy2023

James A Karlowsky, Meredith A Hackel, Mark G Wise, David A Six, Tsuyoshi Uehara, Denis M Daigle, Susan M Cusick, Daniel C Pevear, Greg Moeck, Daniel F Sahm

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Review
  3. Treatment Options for Metallo-Beta-Lactamase-ProducingInternational journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. [New antimicrobial substances to combat increasing resistance].Innere Medizin (Heidelberg, Germany) · 2026
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. In vitro activity and resistance mechanisms of novel antimicrobial agents against metallo-β-lactamase producers.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

James A KarlowskyIHMA, Schaumburg, Illinois, USA.
Meredith A HackelIHMA, Schaumburg, Illinois, USA.ORCID 0000-0003-3339-2701
Mark G WiseIHMA, Schaumburg, Illinois, USA.
David A SixVenatorx Pharmaceuticals, Inc., Malvern, Pennsylvania, USA.
Tsuyoshi UeharaVenatorx Pharmaceuticals, Inc., Malvern, Pennsylvania, USA.
Denis M DaigleVenatorx Pharmaceuticals, Inc., Malvern, Pennsylvania, USA.ORCID 0000-0001-9287-2997
Susan M CusickVenatorx Pharmaceuticals, Inc., Malvern, Pennsylvania, USA.
Daniel C PevearVenatorx Pharmaceuticals, Inc., Malvern, Pennsylvania, USA.
Greg MoeckVenatorx Pharmaceuticals, Inc., Malvern, Pennsylvania, USA.
Daniel F SahmIHMA, Schaumburg, Illinois, USA.
VenatoRx Pharmaceuticals (United States) · USUniversity of Manitoba · CA

Funding

NIAID NIH HHS HHSN272201300019CNIAID NIH HHS HHSN272201300019IWellcome TrustWellcome Trust 101999/Z/13/Z
6 · The paper itself

Abstract

Taniborbactam is a novel cyclic boronate β-lactamase inhibitor in clinical development in combination with cefepime. We assessed the

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialAzabicyclo Compoundsbeta-LactamasesBorinic AcidsBoronic AcidsCarboxylic AcidsCefepimeCephalosporinsGram-Negative BacteriaMeropenemMicrobial Sensitivity TestsPseudomonas aeruginosaTazobactamAnti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamasesBorinic AcidsBoronic AcidsCarboxylic AcidsCefepimeceftolozaneceftolozane, tazobactam drug combinationCephalosporinsMeropenemtaniborbactamTazobactamvaborbactamcarbapenem resistantEnterobacteralesGram-negativemultidrug resistantPseudomonas aeruginosataniborbactamβ-lactamase inhibitor

Identifiers

PMID36541767
PMCPMC9872668
OpenAlexW4312064895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.