Evidence map›Paper›PMID 36541753›Full record

ArticleJournal of clinical microbiology2023

Protein Microarray-Guided Development of a Highly Sensitive and Specific Dipstick Assay for Glanders Serodiagnostics.

Gabriel E Wagner, Andreas Berner, Michaela Lipp, Christian Kohler, Karoline Assig, Sabine Lichtenegger, Muhammad Saqib, Elke Müller, Trung T Trinh, Anne-Marie Gad and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Antibodies toMicroorganisms · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Vaccines · 2024
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 5 countries.

Gabriel E WagnerDiagnostic & Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria.
Andreas Berner *Diagnostic & Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria.
Michaela Lipp *Diagnostic & Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria.
Christian KohlerFriedrich Loeffler Institute for Medical Microbiology, Greifswald, Germany.
Karoline AssigDiagnostic & Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria.
Sabine LichteneggerDiagnostic & Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria.
Muhammad SaqibDepartment of Clinical Medicine and Surgery, University of Agriculture, Faisalabad, Pakistan.
Elke MüllerInfectoGnostics Research Campus, Centre for Applied Research, Jena, Germany.
Trung T TrinhInstitute of Microbiology and Biotechnology, Vietnam National University, Hanoi, Vietnam.
Anne-Marie GadSenova Gesellschaft für Biowissenschaft und Technik mbH, Weimar, Germany.
Hans Hermann SöffingSenova Gesellschaft für Biowissenschaft und Technik mbH, Weimar, Germany.
Ralf EhrichtInfectoGnostics Research Campus, Centre for Applied Research, Jena, Germany.
Karine LaroucauParis Est University, Anses, Animal Health Laboratory, Bacterial zoonosis UnitMaisons-Alfort Cedex, France.
Ivo SteinmetzDiagnostic & Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria.ORCID 0000-0003-0510-7336
Medical University of Graz · ATLeibniz Institute of Photonic Technology · DEFriedrich-Loeffler-Institut · DEParis-Est Sup · FRUniversity of Agriculture Faisalabad · PKVietnam National University, Hanoi · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burkholderia mallei, the causative agent of glanders, is a clonal descendant of Burkholderia pseudomallei, the causative agent of melioidosis, which has lost its environmental reservoir and has a restricted host range. Despite limitations in terms of sensitivity and specificity, complement fixation is still the official diagnostic test for glanders. Therefore, new tools are needed for diagnostics and to study the B. mallei epidemiology. We recently developed a highly sensitive serodiagnostic microarray test for human melioidosis based on the multiplex detection of B. pseudomallei proteins. In this study, we modified our array tests by using anti-horse IgG conjugate and tested sera from B. mallei-infected horses (

Indexed as

Burkholderia malleiBurkholderia pseudomalleiGlandersMelioidosisAnimalsHorsesHumansProtein Array Analysisdiagnostic testglandersimmune responsepoint-of-care testserology

Identifiers

PMID36541753
PMCPMC9879090
OpenAlexW4312045961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.