Trial reportClinical oral implants research2023
Photobiomodulation in dental implant stability and post-surgical healing and inflammation. A randomised double-blind study.
Trial report in Clinical oral implants research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The effect of Photobiomodulation therapy on implant stability in patients receiving dental implants- a systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Clinical efficacy of photobiomodulation therapy in dental implant stability and crestal bone loss in implants placed in healed sites: a systematic review and meta-analysis of randomized clinical trials.Lasers in medical science · 2025Pooled it
- Comparative clinical effects of extraoral photobiomodulation using laser and LED on pain, swelling, and quality of life following impacted mandibular third molar surgery: a randomized split-mouth trial.Lasers in medical science · 2026Trial
- Effect of diode laser biostimulation on implant stability, post-surgical inflammation, and bone healing in immediate implant in the maxillary premolars. A randomized double-blind trial.Clinical oral investigations · 2026Trial
- Evaluation of local and systemic photobiomodulation in only single-implant insertion: a randomized clinical trial.Oral and maxillofacial surgery · 2025Trial
- Low intensity pulsed ultrasound versus low-level laser therapy on peri-implant marginal bone preservation and soft tissue healing following dental implant surgery: a randomized controlled trial.Head & face medicine · 2025Trial
- Photobiomodulation in dental implant stability and post-surgical healing and inflammation. A randomised double-blind study.Clinical oral implants research · 2023Trial
- Photobiomodulation in Dental Implant Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Dentistry journal · 2026Review
- Article
- Effects of Dual Wavelength Photobiomodulation on Osseointegration in Grafted Areas.Lasers in surgery and medicine · 2026Article
- Analgesic outcomes of 650 nm versus 810 nm diode laser photobiomodulation after dental implant placement in a randomized controlled trial.Scientific reports · 2026Article
- Photobiomodulation Therapy (PBMT) with Dual-Wavelength Enhances Reduction of Inflammation After Third Molar Extraction Compared with Red Laser PBMT: A Randomized Clinical Trial.Journal of clinical medicine · 2026Article
- Cross-Linked Hyaluronic Acid and Laser Photobiomodulation in Guided Bone Regeneration (GBR): A Case Report Describing a New Combined Technique.Case reports in dentistry · 2026Article
- Simple Custom Led Panel increases Adipogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells through Photobiomodulation.Journal of stem cells & regenerative medicine · 2026Article
- Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances.Signal transduction and targeted therapy · 2025Review
- Photobiomodulation in dental implant stability and post-surgical healing: A clinical study.Bioinformation · 2025Article
- Effect of low-level laser therapy's effectiveness in reducing pain and bone loss around dental implants.Bioinformation · 2025Article
- The Efficacy of Low-Level Laser Therapy on the Healing of Oral Wounds: A Systematic Review.Cureus · 2024Review
- Efficacy of Photobiomodulation in the Management of Pain and Inflammation after Dental Implants: A Randomized Clinical Trial.Journal of clinical medicine · 2024Article
- Photobiomodulation in Ophthalmology: A Comprehensive Review of Bench-to-Bedside Research and Clinical Integration.Cureus · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundThe aim of this randomized clinical trial was to evaluate the effect of diode laser photobiomodulation (PBM) on post-surgical healing, inflammation and implant stability.
methodsForty dental implants were inserted into 13 patients. The implants were randomly divided into two groups. The test group (PBM+) underwent two sessions of PBM (combined diode laser of 630 and 808 nm), the first of which after surgery, and the second, 7 days after the surgical procedure. The control group (PBM-) received simulated laser treatment. The implant stability quotient (ISQ) was determined immediately after the surgical procedure, and 7 days, 4 and 8 weeks later. Post-surgical inflammation was assessed following the criteria described by Bloemen and Cols. Healing was calculated using the healing index (HI).
resultsNo differences were found in terms of the mean values of implant stability between the test and control groups over time. Only two of the implants (18.2%) from the PBM- group were classified with the maximum healing index (HI = 5), whereas in the PBM+ group, nine implants (45%) were classified with the aforementioned index (P < 0.0001). Using the logistic regression, it was determined that the non-application of the laser in the PBM- group caused an OR of 4.333 times of presenting inflammation (IC95% 1.150-16.323; P = 0.030).
conclusionsThe application of 808 nm infra-red laser for bone tissue, and 630 nm for mucosal tissue in two sessions is considered to be an effective way of reducing inflammation and improving early healing. More studies are needed to confirm these results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.