Evidence map›Paper›PMID 36540645›Full record

ArticleEvolutionary applications2022

Microevolutionary mechanism of high-altitude adaptation in Tibetan chicken populations from an elevation gradient.

Hai-An Zhong, Xiao-Yan Kong, Ya-Wen Zhang, Yan-Kai Su, Bo Zhang, Li Zhu, Hua Chen, Xiao Gou, Hao Zhang

Open access · goldAbstract read
In one paragraph

Article in Evolutionary applications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hai-An ZhongNational Engineering Laboratory for Animal Breeding, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology China Agricultural University Beijing China.
Xiao-Yan KongSchool of Life Science and Engineering Foshan University Guangdong China.
Ya-Wen ZhangNational Engineering Laboratory for Animal Breeding, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology China Agricultural University Beijing China.
Yan-Kai SuCenter for Computational Genomics Beijing Institute of Genomics, Chinese Academy of Sciences Beijing China.
Bo ZhangNational Engineering Laboratory for Animal Breeding, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology China Agricultural University Beijing China.
Li ZhuCollege of Animal Science and Technology Yunnan Agricultural University Kunming China.
Hua ChenCenter for Computational Genomics Beijing Institute of Genomics, Chinese Academy of Sciences Beijing China.
Xiao GouSchool of Life Science and Engineering Foshan University Guangdong China.
Hao ZhangNational Engineering Laboratory for Animal Breeding, Beijing Key Laboratory for Animal Genetic Improvement, College of Animal Science and Technology China Agricultural University Beijing China.ORCID https://orcid.org/0000-0003-4093-5647
China Agricultural University · CNChinese Academy of Sciences · CNFoshan University · CNYunnan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an indigenous breed, the Tibetan chicken is found in highland regions and shows physiological adaptations to high altitude; however, the genetic changes that determine these adaptations remain elusive. We assumed that the microevolution of the Tibetan chicken occurred from lowland to highland regions with a continuous elevation range. In this study, we analyzed the genome of 188 chickens from lowland areas to the high-altitude regions of the Tibetan plateau with four altitudinal levels. Phylogenetic analysis revealed that Tibetan chickens are significantly different from other altitude chicken populations. Reconstruction of the demographic history showed that the migration and admixture events of the Tibetan chicken occurred at different times. The genome of the Tibetan chicken was also used to analyze positive selection pressure that is associated with high-altitude adaptation, revealing the well-known candidate gene that participates in oxygen binding (

Indexed as

demographic historyhigh‐altitude adaptationmicroevolutionTibetan chicken

Identifiers

PMID36540645
PMCPMC9753841
OpenAlexW4307757485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.