Evidence map›Paper›PMID 36540385›Full record

ArticleOpen forum infectious diseases2022

Prevalence and Mortality of Infective Endocarditis in Community-Acquired and Healthcare-Associated

Lauge Østergaard, Marianne Voldstedlund, Niels Eske Bruun, Henning Bundgaard, Kasper Iversen, Nana Køber, Anders Dahl, Sandra Chamat-Hedemand, Jeppe Kofoed Petersen, Andreas Dalsgaard Jensen and 11 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 1 country.

Lauge ØstergaardThe Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-3298-1467
Marianne VoldstedlundStatens Serum Institut, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-0419-6114
Niels Eske BruunDepartment of Cardiology, Zealand University Hospital, Roskilde, Denmark.
Henning BundgaardThe Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-0563-7049
Kasper IversenDepartment of Cardiology, Herlev-Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0003-0504-8487
Nana KøberDepartment of Cardiology, Regionshospital Nord, Hjørring, Denmark.
Anders DahlDepartment of Cardiology, Herlev-Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-1605-2601
Sandra Chamat-HedemandDepartment of Cardiology, Zealand University Hospital, Roskilde, Denmark.
Jeppe Kofoed PetersenThe Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-1166-7877
Andreas Dalsgaard JensenThe Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Jens Jørgen ChristensenRegional Department of Clinical Microbiology, Zealand University Hospital, Køge and Institute of Clinical Medicine, University of Copenhagen, Køge, Denmark.
Flemming Schønning RosenvingeDepartment of Clinical Microbiology, Odense University Hospital and Research Unit of Clinical Microbiology, University of Southern Denmark, Odense, Denmark.
Jens Otto JarløvDepartment of Clinical Microbiology, Herlev-Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Claus MoserDepartment of Clinical Microbiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Christian Østergaard AndersenDepartment of Clinical Microbiology, Amager-Hvidovre Hospital, Copenhagen, Denmark.
John CoiaDepartment of Clinical Microbiology, Hospital of South-west Jutland and Institute for Regional Health Research University of South Denmark, Esbjerg, Denmark.
Ea Sofie MarmolinDepartment of Clinical Microbiology, Vejle Hospital, Vejle, Denmark.
Kirstine K SøgaardDepartment of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark.
Lars LemmingDepartment of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.
Lars KøberThe Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-6635-1466
Emil Loldrup FosbølThe Heart Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKAalborg University Hospital · DKAarhus University Hospital · DKAmager Hospital · DKHospital South West Jutland · DKRegionshospital Nordjylland · DKStatens Serum Institut · DKUniversity of Southern Denmark · DKVejle Sygehus · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: First-time SAB was identified from 2010 to 2018 using Danish nationwide registries and categorized into community-acquired (no healthcare contact within 30 days) or healthcare-associated (SAB >48 hours of hospital admission, hospitalization within 30 days, or outpatient hemodialysis). Prevalence of IE (defined from hospital codes) was compared between groups using multivariable adjusted logistic regression analysis. One-year mortality of Results: We identified 5549 patients with community-acquired SAB and 7491 with healthcare-associated SAB. The prevalence of IE was 12.1% for community-acquired and 6.6% for healthcare-associated SAB. Community-acquired SAB was associated with a higher odds of IE as compared with healthcare-associated SAB (odds ratio, 2.12 [95% confidence interval {CI}, 1.86-2.41]). No difference in mortality was observed with 0-40 days of follow-up for community-acquired SAIE as compared with healthcare-associated SAIE (HR, 1.07 [95% CI, .83-1.37]), while with 41-365 days of follow-up, community-acquired SAIE was associated with a lower mortality (HR, 0.71 [95% CI, .53-.95]). Conclusions: Community-acquired SAB was associated with twice the odds for IE, as compared with healthcare-associated SAB. We identified no significant difference in short-term mortality between community-acquired and healthcare-associated SAIE. Beyond 40 days of survival, community-acquired SAIE was associated with a lower mortality.

Indexed as

community-acquiredendocarditishealthcare-associatedinfective endocarditisStaphylococcus aureus bacteremia

Identifiers

PMID36540385
PMCPMC9757695
OpenAlexW4311898320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.