Evidence map›Paper›PMID 36540278›Full record

ReviewBreast cancer (Dove Medical Press)2022

Advances in Single-Cell Sequencing Technology and Its Applications in Triple-Negative Breast Cancer.

Meng Li, Tingting Yan, Miaozhou Wang, Yanqiu Cai, Yingyuan Wei

Open access · goldAbstract readReview
In one paragraph

Review in Breast cancer (Dove Medical Press), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Meng LiGraduate School of Qinghai University, Qinghai University, Xining, Qinghai Province, People's Republic of China.
Tingting YanGraduate School of Qinghai University, Qinghai University, Xining, Qinghai Province, People's Republic of China.
Miaozhou WangGraduate School of Qinghai University, Qinghai University, Xining, Qinghai Province, People's Republic of China.
Yanqiu CaiGraduate School of Qinghai University, Qinghai University, Xining, Qinghai Province, People's Republic of China.
Yingyuan WeiGraduate School of Qinghai University, Qinghai University, Xining, Qinghai Province, People's Republic of China.
Qinghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer and is mainly treated with chemotherapy-based combination therapy. In recent years, with the increasing development of global precision medicine, single-cell sequencing (SCS) has become one of the most promising technologies in the field of biotechnology. Moreover, the related application of this technology in TNBC has been applied and developed. By using SCS to study the heterogeneity of TNBC tumor cells, metastasis, drug resistance mechanisms, mutations, and cloning; it can further guide clinical chemotherapy, targeted therapy, and immunotherapy. To further reflect the importance of SCS in TNBC, this paper elaborated on and summarized the research and application progress of SCS in TNBC.

Indexed as

drug resistanceheterogeneitymetastasisSCSTNBC

Identifiers

PMID36540278
PMCPMC9760048
OpenAlexW4311327005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.