Evidence map›Paper›PMID 36540194›Full record

ArticleNewborn (Clarksville, Md.)

Congenital and Perinatal Varicella Infections.

Srijan Singh, Akash Sharma, Mohammad Mozibur Rahman, Gangajal Kasniya, Akhil Maheshwari, Suresh B Boppana

Open access · bronzeAbstract read
In one paragraph

Article in Newborn (Clarksville, Md.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  3. Article
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  6. Article
  7. Acute pruritic eruption.JAAD case reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Srijan SinghDepartment of Paediatrics, Grant Government Medical College and Sir JJ Hospitals, Mumbai, Maharashtra, India.ORCID 0000-0002-2103-5232
Akash SharmaDepartment of Pediatrics, Sir Padampat Institute of Neonatal and Pediatric Health (SPINPH), SMS Medical College, Jaipur, Rajasthan, India.ORCID 0000-0003-1045-4367
Mohammad Mozibur RahmanInstitute of Child and Mother Health (ICMH), Dhaka, Bangladesh.
Gangajal KasniyaMount Sinai Hospital, Chicago, Illinois, United States of America.
Akhil MaheshwariGlobal Newborn Society, Clarksville, Maryland, United States of America.ORCID 0000-0003-3613-4054
Suresh B BoppanaDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals · INMount Sinai Hospital · USSMS Medical College · INUniversity of Alabama at Birmingham · US

Funding

Congenital CMV and CNS Infection Mechanisms of Protective ImmunityR01AI089956 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI William Jarvis Britt · 2011 to 2026
$7.7M
Project-002U01CA260462 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BOPPANA, SURESH B, BRITT, WILLIAM JARVIS · 2020 to 2023
$4.0M
NCI NIH HHS U01 CA260462NIAID NIH HHS R01 AI089956
6 · The paper itself

Abstract

Varicella-zoster virus (VZV) is a human pathogen of the α-herpesvirus family. Some fetuses infected in utero around 8-20 weeks of pregnancy show signs of congenital varicella syndrome (CVS). Infants born to mothers who develop varicella within 5 days before and 2 days after delivery can experience severe disease with increased mortality. The best diagnostic modality is polymerase chain reaction (PCR), which can be done using vesicular swabs or scrapings, scabs from crusted lesions, tissue from biopsy samples, and cerebrospinal fluid. The prevention and management of varicella infections include vaccination, anti-VZV immunoglobulin, and specific antiviral drugs. In this article, we have reviewed the characteristics of VZV, clinical manifestations, management of perinatal infections, and short- and long-term prognosis.

Indexed as

Congenital varicella syndromeHerpes zosterNeonatal varicellaPostexposure prophylaxisVaricella zoster immunoglobulinVaricella–zoster virusVesicular rash

Identifiers

PMID36540194
PMCPMC9762609
OpenAlexW4303418600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.